Splenogonadal fusion

Splenogonadal Fusion

Splenogonadal fusion specimen

Splenogonadal fusion is a rare congenital anomaly characterized by an abnormal connection between the spleen and the gonads, which are the testes in males and the ovaries in females. This condition can present in two forms: continuous and discontinuous.

Forms of Splenogonadal Fusion

Splenogonadal fusion is classified into two main types:

Continuous Type

In the continuous type, there is a direct anatomical connection between the spleen and the gonad. This connection is typically a fibrous band that may contain splenic tissue. The continuous type is more commonly associated with other congenital anomalies, such as limb defects or cryptorchidism.

Discontinuous Type

In the discontinuous type, there is no direct connection between the spleen and the gonad. Instead, ectopic splenic tissue is found in the gonad or along the path of descent of the gonad. This type is less frequently associated with other anomalies.

Clinical Presentation

Splenogonadal fusion is often asymptomatic and may be discovered incidentally during surgery for other conditions, such as inguinal hernia repair or orchidopexy. In some cases, it may present as a scrotal mass or testicular swelling, leading to a suspicion of a testicular tumor. In females, it may be discovered during evaluation for ovarian masses.

Diagnosis

The diagnosis of splenogonadal fusion is typically made during surgical exploration. Preoperative imaging, such as ultrasound or magnetic resonance imaging (MRI), may suggest the presence of ectopic splenic tissue, but definitive diagnosis often requires histological examination.

Histological section of splenogonadal fusion

Histology

Histological examination of the affected tissue reveals normal splenic architecture, including red and white pulp, within the gonad or along the fibrous band connecting the spleen and gonad. This confirms the diagnosis of splenogonadal fusion.

Treatment

Treatment is not always necessary, especially if the condition is asymptomatic. Surgical intervention may be required if there is suspicion of malignancy or if the condition causes discomfort or other complications. The surgical approach involves excision of the ectopic splenic tissue while preserving gonadal function.

Prognosis

The prognosis for individuals with splenogonadal fusion is generally excellent, particularly when the condition is isolated and not associated with other congenital anomalies. The risk of malignancy in ectopic splenic tissue is extremely low.

Related Pages

• Spleen
• Gonad
• Congenital disorder
• Cryptorchidism
• Testicular tumor