Altumomab pentetate

Altumomab Pentetate is a monoclonal antibody that is used in the field of medicine and biotechnology. It is a type of radioimmunotherapy that is used for the treatment of various types of cancer.

History

Altumomab Pentetate was first developed in the late 20th century as a part of the growing field of monoclonal antibody therapy. This type of therapy uses antibodies to target specific cells, such as cancer cells, and deliver a therapeutic agent to those cells.

Mechanism of Action

Altumomab Pentetate works by binding to a specific antigen on the surface of cancer cells. Once bound, the pentetate portion of the molecule can deliver a radioactive isotope to the cell, which can kill the cell. This targeted approach can help to minimize damage to healthy cells and reduce side effects.

Uses

Altumomab Pentetate is used in the treatment of a variety of cancers, including lung cancer, breast cancer, and colorectal cancer. It is often used in combination with other treatments, such as chemotherapy and radiation therapy.

Side Effects

Like all medications, Altumomab Pentetate can cause side effects. These can include nausea, vomiting, and fatigue. More serious side effects can include anemia, neutropenia, and thrombocytopenia.

Future Research

Research is ongoing into the use of Altumomab Pentetate and other monoclonal antibodies in the treatment of cancer. This includes research into new ways to deliver the therapy, as well as research into new targets for the therapy.