Brodie abscess

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Brodie abscess is a bone infection - a hematogenous osteomyelitis which is subacute.

Brodie Abscess
Brodie Abscess

Incidence[edit | edit source]

It that accounts for 2.5%–42% of primary bone infections.

Patient characteristics[edit | edit source]

The patients are younger than 25 years of age. They usually present with joint pain and localized swelling.

Signs and symptoms[edit | edit source]

Signs and symptoms of systemic disease are frequently absent and usually only have joint pain and swelling.

AP radiograph of the distal tibia showing a lytic lesion proved to be a subacute staphlococcal osteomyelitis.
Brodie abscess - subacute staphlococcal osteomyelitis.

Cause[edit | edit source]

  • Staphylococcus aureus (30%–60%)
  • Pseudomonas (5%)
  • Klebsiella (5%) and
  • Coagulase-negative Staphylococcus (5%) are causative organisms.

Culture negative[edit | edit source]

20% of cultures are negative for these organisms.

Brodie Abscess MRI
Brodie Abscess MRI

Radiology[edit | edit source]

  • Radiographically, an intramedullary area of central lucency with sclerotic margins is characteristic.

Differential diagnosis[edit | edit source]

Diagnosis[edit | edit source]

X-rays, CT scan, MRI, blood cultures etc.

Treatment[edit | edit source]

  • A course of systemic antibiotics, surgical débridement.
  • Sometimes bone grafting maybe required a large cavity requires stabilization.


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Contributors: Prab R. Tumpati, MD