Chenodeoxycholic acid
Chenodeoxycholic acid is a prominent bile acid, recognized for its white crystalline structure and its inability to dissolve in water. It is one of the principal organic acids manufactured by the liver and plays a pivotal role in human bile acid composition. While it remains insoluble in water, chenodeoxycholic acid is soluble in both alcohol and acetic acid.
Synthesis[edit | edit source]
Chenodeoxycholic acid originates within the liver, where it is synthesized from cholesterol. The precise biochemical pathway involves multiple enzymatic reactions, ensuring the conversion of cholesterol to this particular bile acid.
Function[edit | edit source]
Within the human bile acid composition, chenodeoxycholic acid and cholic acid hold significant importance. They are pivotal for digestion and absorption processes. On the other hand, some other mammals predominantly produce deoxycholic acid, which has its distinct set of functions.
Uses[edit | edit source]
Chenodeoxycholic acid, owing to its intrinsic properties, finds use in various medical applications:
- Hepatitis C Treatment: Giaconda, an Australian biotech firm, has innovated a therapeutic strategy for treating Hepatitis C infections. This involves a combination of chenodeoxycholic acid and bezafibrate. The synergistic effect of both components offers a potentially effective treatment modality against the infection.
Chemical Properties[edit | edit source]
The salts of chenodeoxycholic acid are referred to as chenodeoxycholates. Their formation is integral to many biological processes, particularly in the digestive system.
Interactions with Other Bile Acids[edit | edit source]
Given the diverse range of bile acids produced within the body, chenodeoxycholic acid frequently interacts with them. These interactions influence various physiological processes, including lipid digestion and absorption in the intestines.
Safety and Precautions[edit | edit source]
When working with or consuming compounds like chenodeoxycholic acid, certain safety guidelines need to be adhered to. It is essential to understand its potential effects on the body, possible side effects, and any contraindications.
See Also[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
