Chronic liver failure

Chronic liver failure is a long-term, progressive deterioration of liver function. It is characterized by the loss of liver cells and the inability of the liver to perform its normal functions, such as detoxifying harmful substances in the body, purifying blood, and synthesizing vital nutrients.

Causes

Chronic liver failure is usually caused by long-term exposure to toxic substances or viral infections. The most common causes include hepatitis B, hepatitis C, and long-term alcohol consumption. Other causes can include autoimmune hepatitis, diseases that cause blockage of the bile ducts (such as primary biliary cirrhosis and primary sclerosing cholangitis), and genetic diseases such as Wilson's disease or hemochromatosis.

Symptoms

The symptoms of chronic liver failure may include fatigue, nausea, loss of appetite, and jaundice (yellowing of the skin and eyes). As the disease progresses, complications may develop, including cirrhosis, liver cancer, and liver failure.

Diagnosis

Diagnosis of chronic liver failure involves a series of tests, including blood tests, imaging tests, and sometimes a liver biopsy. Blood tests can reveal liver function abnormalities and help identify the cause of the condition. Imaging tests, such as an ultrasound, CT scan, or MRI, can show the size and shape of the liver and reveal any abnormalities. A liver biopsy can confirm the diagnosis and help determine the severity of the disease.

Treatment

Treatment for chronic liver failure depends on the underlying cause. It may include lifestyle changes, medications, or in severe cases, liver transplantation. Lifestyle changes may include avoiding alcohol, eating a healthy diet, and exercising regularly. Medications can help control the symptoms and slow the progression of the disease. In severe cases, a liver transplant may be necessary.

Prognosis

The prognosis for chronic liver failure depends on the severity of the disease and the patient's overall health. Early detection and treatment can improve the prognosis.

See also

• Liver disease
• Liver transplantation
• Hepatitis

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