Idiopathic nephrotic syndrome

From WikiMD's Wellness Encyclopedia

Idiopathic Nephrotic Syndrome is a kidney disorder often characterized by heavy proteinuria, hypoalbuminemia, and edema. The term "idiopathic" signifies that the exact cause of the syndrome is unknown.

Overview[edit | edit source]

Idiopathic Nephrotic Syndrome is a type of nephrotic syndrome that occurs without an apparent underlying cause. It is a clinical syndrome that is characterized by heavy proteinuria, which is the presence of excess proteins in the urine. This leads to hypoalbuminemia, a condition where there is a low level of albumin in the blood, and edema, which is swelling caused by fluid accumulation in the body's tissues.

Symptoms[edit | edit source]

The symptoms of Idiopathic Nephrotic Syndrome can vary from person to person. However, common symptoms include edema, particularly in the legs and around the eyes, fatigue, weight gain due to fluid retention, and foamy urine due to excess protein (proteinuria).

Diagnosis[edit | edit source]

The diagnosis of Idiopathic Nephrotic Syndrome is typically made based on the presence of the characteristic symptoms, along with laboratory tests that show heavy proteinuria and hypoalbuminemia. In some cases, a kidney biopsy may be performed to examine the kidney tissue under a microscope and help confirm the diagnosis.

Treatment[edit | edit source]

The treatment of Idiopathic Nephrotic Syndrome primarily involves managing the symptoms and preventing complications. This may include medications to reduce proteinuria and edema, dietary modifications to limit protein and salt intake, and in some cases, treatment with immunosuppressive drugs to reduce inflammation in the kidneys.

Prognosis[edit | edit source]

The prognosis for individuals with Idiopathic Nephrotic Syndrome can vary widely. Some individuals may experience a complete recovery, while others may have persistent proteinuria and progress to chronic kidney disease or end-stage renal disease.

See Also[edit | edit source]





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Contributors: Prab R. Tumpati, MD