Mammoplasia

Enlargement of breast tissue

Mammoplasia
Synonyms	Breast enlargement, Macromastia
Pronounce	/ˌmæməˈpleɪʒə/
Field	Endocrinology, Plastic surgery, Obstetrics
Symptoms	Enlargement of one or both breasts
Complications	Back pain, neck pain, posture issues (in severe cases)
Onset	Puberty, pregnancy, or due to hormonal changes
Duration	Variable; temporary or permanent depending on cause
Types	Physiological, pathological, iatrogenic
Causes	Hormonal fluctuations, pregnancy, puberty, medications (e.g., hormone therapy), genetic predisposition
Risks	Hormone therapy, endocrine disorders, pregnancy, obesity
Diagnosis	Clinical examination, patient history, imaging if needed
Differential diagnosis	Gigantomastia, Gynecomastia (in males), breast tumors
Prevention	None in physiological cases; monitor hormone levels if medically induced
Treatment	Observation, supportive garments; reduction mammoplasty in symptomatic cases
Medication	Hormonal modulation if medically indicated
Prognosis	Good; often benign and self-limited
Frequency	Common, particularly during puberty and pregnancy
Deaths	Not directly associated

Mammoplasia refers to the enlargement of breast tissue. This condition can occur in both males and females and can be due to various physiological, pathological, or pharmacological factors.

Physiological Causes

Mammoplasia is a normal physiological process during certain life stages. In females, it is most commonly associated with puberty, pregnancy, and lactation.

Puberty

During puberty, the female body undergoes significant hormonal changes, leading to the development of secondary sexual characteristics, including breast enlargement. This is primarily due to the action of estrogen and progesterone, which stimulate the growth of mammary glands and the deposition of adipose tissue in the breasts.

Pregnancy

During pregnancy, mammoplasia occurs as the body prepares for lactation. The hormones estrogen, progesterone, and prolactin play crucial roles in this process, leading to the proliferation of glandular tissue and an increase in breast size.

Lactation

After childbirth, the breasts may further enlarge due to the production of milk in the mammary glands. This is a temporary form of mammoplasia that subsides after the cessation of breastfeeding.

Pathological Causes

Mammoplasia can also occur due to pathological conditions.

Gynecomastia

In males, mammoplasia is often referred to as gynecomastia, which is the enlargement of breast tissue due to an imbalance between estrogen and testosterone. This condition can be caused by various factors, including hormonal imbalances, medications, and liver disease.

Breast Tumors

Certain breast tumors, both benign and malignant, can lead to localized or generalized enlargement of breast tissue. Conditions such as fibroadenoma or breast cancer may present with mammoplasia as a symptom.

Pharmacological Causes

Certain medications can induce mammoplasia as a side effect. These include:

• Hormone replacement therapy
• Anabolic steroids
• Antipsychotics
• Antidepressants

Management

The management of mammoplasia depends on the underlying cause. In physiological cases, no treatment is necessary. For pathological or pharmacological causes, addressing the underlying condition or adjusting medication may be required. In some cases, surgical intervention such as breast reduction surgery may be considered.

Related pages

• Breast development
• Gynecomastia
• Breast cancer
• Hormonal therapy

External links

Classification	ICD-10: N62
External resources

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