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Template:Chemotherapeutic agents
From WikiMD.com - Food, Medicine & Wellness Encyclopedia
Contents
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v
t
e
Intracellular
chemotherapeutic agents
/
antineoplastic agents
(
L01
)
SPs
/
MIs
(
M phase
)
Block
microtubule
assembly
Vinca alkaloids
(
Vinblastine
#
Vincristine
#
Vindesine
Vinflunine
§
Vinorelbine
#
)
Block microtubule disassembly
Taxanes
(
Cabazitaxel
Docetaxel
#
Larotaxel
Ortataxel
†
Paclitaxel
#
Tesetaxel
)
Epothilones
(
Ixabepilone
)
DNA replication
inhibitor
DNA precursors/
antimetabolites
(
S phase
)
Folic acid
Dihydrofolate reductase inhibitor
(
Aminopterin
Methotrexate
#
Pemetrexed
Pralatrexate
)
Thymidylate synthase inhibitor
(
Pemetrexed
Raltitrexed
)
Purine
Adenosine deaminase inhibitor
(
Pentostatin
)
Halogenated
/
ribonucleotide reductase inhibitors
(
Cladribine
Clofarabine
Fludarabine
)
Nelarabine
Rabacfosadine
Thiopurine
(
Mercaptopurine
#
Tioguanine
#
)
Pyrimidine
Thymidylate synthase inhibitor
(
Capecitabine
#
Carmofur
Doxifluridine
Floxuridine
Fluorouracil
#
Tegafur
(
+gimeracil/oteracil
))
DNA polymerase inhibitor
(
Cytarabine
#
+daunorubicin
)
Ribonucleotide reductase inhibitor
(
Gemcitabine
#
)
Hypomethylating agent
(
Azacitidine
Decitabine
)
Deoxyribonucleotide
Ribonucleotide reductase inhibitor
(
Hydroxycarbamide
#
)
Topoisomerase inhibitors
(
S phase
)
I
Camptotheca
(
Belotecan
Camptothecin
Cositecan
†
Etirinotecan pegol
†
Exatecan
Gimatecan
Irinotecan
#
Lurtotecan
‡
Rubitecan
‡
Silatecan
§
Topotecan
)
II
Podophyllum
(
Etoposide
#
Teniposide
)
II
+
Intercalation
Anthracyclines
(
Aclarubicin
Amrubicin
†
Daunorubicin
#
(
+cytarabine
)
Doxorubicin
#
Epirubicin
Idarubicin
Pirarubicin
Valrubicin
Zorubicin
)
Anthracenediones
(
Losoxantrone
Mitoxantrone
Pixantrone
)
Amsacrine
Bisantrene
Crisnatol
Menogaril
§
Crosslinking of DNA
(
CCNS
)
Alkylating
Nitrogen mustards
:
Bendamustine
#
Chlormethine
Cyclophosphamide
#
(
Ifosfamide
#
Trofosfamide
)
Chlorambucil
#
Melphalan
(
Melphalan flufenamide
)
Prednimustine
Uramustine
Nitrosoureas
:
Carmustine
Fotemustine
Lomustine
(
Semustine
)
Nimustine
Ranimustine
Streptozocin
Alkyl sulfonates
:
Busulfan
(
Mannosulfan
Treosulfan
)
Aziridines
:
Carboquone
Thiotepa
Triaziquone
Triethylenemelamine
Platinum-based
Carboplatin
#
Cisplatin
#
Dicycloplatin
Nedaplatin
Oxaliplatin
#
Satraplatin
Nonclassical
Altretamine
Hydrazines
(
Procarbazine
#
)
Etoglucid
Mitobronitol
Pipobroman
Triazenes
(
Dacarbazine
#
Mitozolomide
§
Temozolomide
)
Intercalation
Streptomyces
(
Dactinomycin
#
Bleomycin
#
Mitomycins
Plicamycin
)
Photosensitizers
/
PDT
Aminolevulinic acid
Efaproxiral
Methyl aminolevulinate
Padeliporfin
Porphyrin derivatives
(
Porfimer sodium
Talaporfin
Temoporfin
Verteporfin
)
Other
Enzyme inhibitors
FI
(
Tipifarnib
§
)
CDK
inhibitors
(
Abemaciclib
Alvocidib
†
Palbociclib
Ribociclib
Seliciclib
†
)
PrI
Bortezomib
Carfilzomib
Oprozomib
Ixazomib
PhI
(
Anagrelide
)
IMPDI
(
Tiazofurin
§
)
LI
(
Masoprocol
)
PARP inhibitor
(
Fuzuloparib
Niraparib
+abiraterone acetate
Olaparib
Rucaparib
)
HDAC
(
Belinostat
Entinostat
Panobinostat
Romidepsin
Vorinostat
)
PIKI
(Pi3K)
(
Alpelisib
Copanlisib
‡
Duvelisib
Idelalisib
Inavolisib
Umbralisib
‡
)
IDH
(
Enasidenib
Ivosidenib
Olutasidenib
Vorasidenib
)
Receptor antagonists
ERA
(
Atrasentan
)
Retinoid X receptor
(
Bexarotene
)
Sex steroid
(
Testolactone
)
Other/ungrouped
Adagrasib
Aflibercept
Arsenic trioxide
Asparagine depleters
(
Asparaginase
#
/
Pegaspargase
)
Axicabtagene ciloleucel
Belzutifan
Bexarotene
Brexucabtagene autoleucel
Celecoxib
Ciltacabtagene autoleucel
Demecolcine
Denileukin diftitox
Eflornithine
Elesclomol
§
Elsamitrucin
Epacadostat
Eribulin
Estramustine
Glasdegib
Idecabtagene vicleucel
Imetelstat
Lifileucel
Lisocabtagene maraleucel
Lonidamine
Lucanthone
Lurbinectedin
Mitoguazone
Mitotane
Nadofaragene firadenovec
Navitoclax
Obecabtagene autoleucel
Oblimersen
†
Omacetaxine mepesuccinate
Plitidepsin
Tabelecleucel
Retinoids
(
Alitretinoin
Tretinoin
#
)
Selinexor
Sitimagene ceradenovec
Sotorasib
Tagraxofusp
Talimogene laherparepvec
Tazemetostat
Tebentafusp
Tiazofurine
Tigilanol tiglate
Tisagenlecleucel
Trabectedin
Veliparib
Venetoclax
Verdinexor
Vosaroxin
#
WHO-EM
‡
Withdrawn
from market
Clinical trials
:
†
Phase III
§
Never to phase III