Alza

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Alza is a pharmaceutical and medical systems company that was founded in 1968. The company is known for its innovative drug delivery systems, including oral, transdermal, and implantable technologies. Alza was acquired by Johnson & Johnson in 2001.

History[edit | edit source]

Alza was founded by Dr. Alejandro Zaffaroni in 1968. The company's name is derived from the first two letters of Zaffaroni's first and last names. Zaffaroni was a pioneer in the field of drug delivery systems and his work at Alza led to the development of many innovative products.

In 2001, Alza was acquired by Johnson & Johnson, a multinational corporation that produces medical devices, pharmaceuticals, and consumer packaged goods. The acquisition allowed Johnson & Johnson to expand its portfolio of pharmaceutical products and leverage Alza's expertise in drug delivery systems.

Products[edit | edit source]

Alza has developed a number of innovative drug delivery systems. These include:

  • Oral systems: Alza developed the OROS (Osmotic [Controlled] Release Oral [Delivery] System) technology, which allows for the controlled release of drugs over a 24-hour period. This technology is used in a number of medications, including Concerta for ADHD and Procardia XL for angina and hypertension.
  • Transdermal systems: Alza is also known for its transdermal patch technologies, which deliver medication through the skin. Examples include the Duragesic patch for chronic pain and the Nicoderm CQ patch for smoking cessation.
  • Implantable systems: Alza has developed implantable drug delivery systems, such as the Viadur implant for prostate cancer, which delivers a steady dose of medication over a 12-month period.

Impact[edit | edit source]

Alza's innovative drug delivery systems have had a significant impact on the pharmaceutical industry. By allowing for controlled, sustained release of medications, these systems can improve patient compliance, reduce side effects, and increase the effectiveness of treatments.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD