Sporanox
Sporanox (also known as Itraconazole) is a triazole antifungal medication used to treat a variety of fungal infections. It is produced by Janssen Pharmaceutica, a pharmaceutical company based in Belgium.
Indications[edit | edit source]
Sporanox is primarily used to treat a range of fungal infections, including blastomycosis, histoplasmosis, aspergillosis, and onychomycosis. It is also used in the treatment of candidiasis, particularly in patients who are immunocompromised.
Mechanism of Action[edit | edit source]
Sporanox works by inhibiting the fungal cytochrome P-450 enzyme. This prevents the conversion of lanosterol to ergosterol, disrupting the synthesis of the fungal cell membrane.
Side Effects[edit | edit source]
Common side effects of Sporanox include nausea, vomiting, diarrhea, rash, and edema. More serious side effects can include liver damage, heart failure, and negative interactions with other medications.
Contraindications[edit | edit source]
Sporanox is contraindicated in patients with known hypersensitivity to itraconazole. It should also not be used in patients with congestive heart failure or with a history of liver disease.
Interactions[edit | edit source]
Sporanox can interact with a number of other medications, including certain antacids, antihistamines, and antiretrovirals. It is important for patients to inform their healthcare provider of all medications they are currently taking.
See Also[edit | edit source]
References[edit | edit source]
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