Bay R 1531

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Bay R 1531 is a chemical compound that belongs to the class of phenylpiperazines. It is a potent and selective 5-HT1A receptor antagonist, which means it blocks the action of serotonin at the 5-HT1A receptor in the brain. This makes it a useful tool in the research of serotonin-related conditions such as depression, anxiety, and schizophrenia.

Chemistry[edit | edit source]

Bay R 1531 is a phenylpiperazine, a class of compounds that contain a piperazine ring substituted with a phenyl group. The chemical structure of Bay R 1531 also includes a benzodioxolyl group, which contributes to its high affinity for the 5-HT1A receptor.

Pharmacology[edit | edit source]

As a 5-HT1A receptor antagonist, Bay R 1531 blocks the action of serotonin at this receptor. The 5-HT1A receptor is one of several types of serotonin receptors in the brain, and it is involved in a variety of physiological processes, including mood regulation, anxiety, and cognition.

Clinical significance[edit | edit source]

The ability of Bay R 1531 to selectively block the 5-HT1A receptor makes it a valuable tool in the research of conditions that are thought to involve this receptor. These include depression, anxiety, and schizophrenia, among others. By studying the effects of Bay R 1531, researchers can gain insights into the role of the 5-HT1A receptor in these conditions and potentially develop new treatments.

See also[edit | edit source]

Template:Chemical compounds Template:Phenylpiperazines Template:5-HT1A antagonists

Bay R 1531 Resources
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Contributors: Prab R. Tumpati, MD