Folacin

Folacin is a water-soluble vitamin belonging to the B-complex group, also known as Vitamin B9 or Folic Acid. It is essential for the body's growth and development, playing a crucial role in the synthesis and repair of DNA and RNA, the production of red blood cells, and the prevention of certain types of anemia.

Functions

Folacin is involved in numerous bodily functions:

• DNA and RNA Synthesis: Folacin is necessary for the production and maintenance of new cells, especially during periods of rapid cell division and growth such as infancy and pregnancy. This is because DNA and RNA synthesis relies on folacin to produce the building blocks of these genetic materials.

• Red Blood Cell Production: Folacin is involved in the production of red blood cells in the bone marrow. A deficiency in folacin can lead to megaloblastic anemia, a condition where the body produces abnormally large, immature red blood cells.

• Prevention of Birth Defects: Adequate folacin intake during pregnancy can prevent major birth defects of the baby's brain and spine.

Sources

Folacin can be found in a variety of foods:

• Leafy green vegetables such as spinach and turnip greens
• Fruits and fruit juices, especially oranges and orange juice
• Beans, peas, and lentils
• Meat such as liver and poultry
• Seafood
• Eggs
• Fortified grains and cereals

Deficiency

Folacin deficiency can lead to a variety of health problems:

• Megaloblastic Anemia
• Birth defects in pregnant women
• Elevated homocysteine levels, which can increase the risk of heart disease
• Changes in skin, hair, or fingernail color

Recommended Intake

The recommended dietary allowance (RDA) for folacin varies depending on age, sex, and life stage. For adults, the RDA is 400 micrograms of dietary folate equivalents (DFEs) per day.

See Also

• Vitamin B9
• Folic Acid
• Megaloblastic Anemia

Folacin Resources
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