Urticarial vasculitis
(Redirected from McDuffie syndrome)
Urticarial Vasculitis is a rare form of vasculitis that affects the skin, causing urticaria (hives) and inflammation of the small blood vessels. The condition can be categorized into two types: normocomplementemic and hypocomplementemic, with the latter being more severe and associated with systemic symptoms such as joint pain and abdominal pain.
Symptoms[edit | edit source]
The primary symptom of Urticarial Vasculitis is the presence of urticaria, or hives, which are red, itchy welts on the skin. These hives are different from those in ordinary urticaria, as they last longer (more than 24 hours), may leave a bruise and often hurt or burn. Other symptoms can include fever, joint pain, and abdominal pain.
Causes[edit | edit source]
The exact cause of Urticarial Vasculitis is unknown. However, it is thought to be an autoimmune disease, where the body's immune system attacks its own tissues. It can also be associated with other diseases such as lupus, cancer, and hepatitis.
Diagnosis[edit | edit source]
Diagnosis of Urticarial Vasculitis is based on the clinical symptoms and a skin biopsy, which shows inflammation of the small blood vessels (vasculitis). Blood tests may also be done to check for other associated diseases.
Treatment[edit | edit source]
Treatment of Urticarial Vasculitis is aimed at controlling the symptoms and preventing complications. This may include antihistamines for the itching, nonsteroidal anti-inflammatory drugs for pain, and corticosteroids to reduce inflammation. In severe cases, other immunosuppressive drugs may be used.
See also[edit | edit source]
Urticarial vasculitis Resources | |
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Contributors: Prab R. Tumpati, MD