1-Hexacosanol

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1-Hexacosanol, also known as hexacosyl alcohol, is a fatty alcohol with the chemical formula C26H54O. It is a member of the long-chain aliphatic alcohols, which are compounds consisting of long, straight chains of carbon atoms with a hydroxyl group (-OH) attached at one end. 1-Hexacosanol is a white, waxy solid at room temperature and is insoluble in water but soluble in organic solvents such as ethanol and diethyl ether.

Properties and Structure[edit | edit source]

1-Hexacosanol has a molecular weight of 382.71 g/mol and melts at a temperature of about 79.8°C. Its structure consists of a long hydrocarbon chain (26 carbon atoms in length) with a single hydroxyl group attached to the first carbon atom, making it a primary alcohol. This structure contributes to its physical properties, such as its high melting point and waxy nature.

Sources and Production[edit | edit source]

1-Hexacosanol can be found naturally in various plants and is often extracted from the waxy coatings of leaves and fruits. It can also be synthesized through the hydrogenation of hexacosanoic acid or its esters.

Applications[edit | edit source]

1-Hexacosanol has several industrial and pharmaceutical applications. In the cosmetic industry, it is used as an ingredient in skincare products due to its moisturizing properties. It also serves as a feedstock for the synthesis of other chemicals and as a phase change material in thermal energy storage systems due to its high latent heat capacity.

In the pharmaceutical field, research has suggested that 1-Hexacosanol may have potential benefits in improving physical stamina and reducing fatigue by influencing the metabolism of fatty acids in the liver. However, further studies are needed to fully understand its mechanisms and potential therapeutic uses.

Health and Safety[edit | edit source]

As with many chemical substances, the handling of 1-Hexacosanol requires caution. While it is generally considered to be of low toxicity, direct contact with the skin or eyes may cause irritation. Therefore, appropriate personal protective equipment (PPE) should be worn when handling this compound.

Environmental Impact[edit | edit source]

The environmental impact of 1-Hexacosanol is considered to be low. Being a naturally occurring substance, it is biodegradable and unlikely to accumulate in the environment. However, as with all chemical substances, responsible disposal practices should be followed.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD