3,7,8,2'-Tetrahydroxyflavone

3,7,8,2'-Tetrahydroxyflavone is a type of flavonoid, a class of plant secondary metabolites known for their diverse biological activities. This compound is characterized by its four hydroxyl groups attached to the flavone backbone, specifically at the 3, 7, 8, and 2' positions.

Chemical Structure and Properties

3,7,8,2'-Tetrahydroxyflavone belongs to the flavone subclass of flavonoids, which are distinguished by a 15-carbon skeleton consisting of two phenyl rings (A and B) and a heterocyclic pyran ring (C). The presence of hydroxyl groups at specific positions on the flavone structure can significantly influence the compound's solubility, reactivity, and biological activity.

Molecular Formula

The molecular formula of 3,7,8,2'-Tetrahydroxyflavone is C15H10O6.

Molecular Weight

The molecular weight of this compound is approximately 286.24 g/mol.

Chemical Nomenclature

The IUPAC name for 3,7,8,2'-Tetrahydroxyflavone is 3,7,8,2'-Tetrahydroxy-2-phenyl-4H-chromen-4-one.

Biological Activity

Flavonoids, including 3,7,8,2'-Tetrahydroxyflavone, are known for their antioxidant properties. They can scavenge free radicals and chelate metal ions, thereby protecting cells from oxidative stress. This particular flavone may also exhibit anti-inflammatory, anti-cancer, and neuroprotective activities, although specific studies on 3,7,8,2'-Tetrahydroxyflavone are limited.

Antioxidant Activity

The hydroxyl groups in 3,7,8,2'-Tetrahydroxyflavone contribute to its ability to donate hydrogen atoms, neutralizing free radicals and reducing oxidative damage in biological systems.

Potential Health Benefits

Research into flavonoids suggests potential benefits in reducing the risk of chronic diseases such as cardiovascular disease, cancer, and neurodegenerative disorders. However, more research is needed to fully understand the specific effects of 3,7,8,2'-Tetrahydroxyflavone.

Sources and Occurrence

Flavonoids are widely distributed in the plant kingdom, found in fruits, vegetables, and certain beverages like tea and wine. The specific occurrence of 3,7,8,2'-Tetrahydroxyflavone in nature is not well-documented, and it may be present in trace amounts in certain plant species.

Synthesis and Derivatives

3,7,8,2'-Tetrahydroxyflavone can be synthesized in the laboratory through various chemical reactions involving the modification of the flavone core structure. Derivatives of this compound can be created by altering the number and position of hydroxyl groups, which may lead to changes in biological activity.

Research and Applications

Ongoing research is exploring the potential applications of flavonoids in medicine, nutrition, and cosmetics. The antioxidant and anti-inflammatory properties of compounds like 3,7,8,2'-Tetrahydroxyflavone make them candidates for further study in the prevention and treatment of various diseases.

Also see

• Flavonoid
• Antioxidant
• Oxidative stress
• Plant secondary metabolites