Cholestatic jaundice

Cholestatic jaundice is a medical condition characterized by the impairment or cessation of bile flow, which results in the accumulation of bile constituents in the blood and tissues, leading to jaundice. This condition can be caused by a variety of diseases and conditions that affect the liver, gallbladder, and bile ducts.

Causes

Cholestatic jaundice can be caused by a number of conditions, including hepatitis, cirrhosis, gallstones, and cancers of the liver or bile ducts. Certain medications can also cause cholestatic jaundice, as can pregnancy in rare cases.

Symptoms

The primary symptom of cholestatic jaundice is a yellowing of the skin and eyes, known as jaundice. Other symptoms can include dark urine, pale stools, and itching. In severe cases, cholestatic jaundice can lead to serious complications, including liver failure and sepsis.

Diagnosis

Diagnosis of cholestatic jaundice typically involves a combination of history taking, physical examination, and laboratory tests. Imaging studies such as ultrasound, CT scan, and MRI may also be used to identify the cause of the jaundice.

Treatment

Treatment for cholestatic jaundice depends on the underlying cause. This can involve medication to treat the cause of the jaundice, surgery to remove blockages in the bile ducts, or in severe cases, a liver transplant.

See also

• Jaundice
• Hepatitis
• Cirrhosis
• Gallstones
• Liver transplant

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