Compound 14

Compound 14

Compound 14 is a synthetic small molecule that has garnered interest in the field of metabolic research due to its potential effects on energy metabolism and obesity. It is known to act as an activator of the AMP-activated protein kinase (AMPK), a crucial enzyme involved in cellular energy homeostasis.

Chemical Structure and Properties

Compound 14 is characterized by its unique chemical structure, which allows it to interact with the AMPK enzyme. The precise molecular formula and structure are proprietary, but it is known to be a derivative of thienopyridone compounds. Its molecular weight, solubility, and stability under various conditions are key factors in its biological activity.

Mechanism of Action

Compound 14 functions primarily by activating AMPK, a central regulator of energy balance at both the cellular and whole-body levels. AMPK activation leads to the stimulation of catabolic pathways that generate ATP, while inhibiting anabolic pathways that consume ATP. This shift in energy balance can result in increased glucose uptake, enhanced fatty acid oxidation, and improved insulin sensitivity.

Biological Effects

Research has shown that Compound 14 can mimic the effects of exercise by activating AMPK, leading to increased glucose uptake in muscle cells and enhanced lipid metabolism. In animal models, administration of Compound 14 has been associated with reduced body weight and improved metabolic profiles, making it a potential therapeutic agent for treating metabolic disorders such as obesity and type 2 diabetes.

Clinical Implications

While the preclinical data on Compound 14 is promising, further research is needed to evaluate its safety and efficacy in humans. Clinical trials are necessary to determine the appropriate dosing, potential side effects, and long-term impacts of Compound 14 on human metabolism.

Research and Development

Ongoing studies are exploring the potential of Compound 14 as a therapeutic agent. Researchers are investigating its effects in various models of metabolic disease, as well as its potential synergistic effects when combined with other metabolic modulators.

Also see

• AMP-activated protein kinase
• Metabolic syndrome
• Obesity
• Type 2 diabetes
• Fatty acid oxidation

Resources

Latest articles - Compound 14

• Most recent articles
• Ongoing trials

Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Compound 14 for any updates.

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