Limbus
Limbus is a border or edge that is often referred to in medical terminology. In ophthalmology, the limbus is the border between the cornea and the sclera. The limbus is a crucial area of the eye as it is responsible for the regeneration of the cornea.
Anatomy[edit | edit source]
The limbus is located at the junction of the cornea and the sclera. It is a complex structure that is composed of several different tissues. The limbus contains the corneal epithelial stem cells which are essential for the maintenance and repair of the corneal surface.
Function[edit | edit source]
The primary function of the limbus is to act as a barrier to prevent the invasion of the conjunctival epithelial cells onto the cornea. It also plays a crucial role in the maintenance of the corneal transparency by preventing the vascularization of the cornea.
Clinical significance[edit | edit source]
Damage to the limbus can lead to a condition known as limbal stem cell deficiency (LSCD). This condition can result in pain, loss of vision, and may require a limbal stem cell transplantation for treatment.
See also[edit | edit source]
References[edit | edit source]
| Fibrous tunic (outer) |
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| Uvea/vascular tunic (middle) |
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| Retina (inner) |
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| Anatomical regions of the eye |
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Contributors: Prab R. Tumpati, MD
