Mental retardation, unexplained

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Mental Retardation, Unexplained is a term historically used to describe a condition characterized by below-average intellectual function and a lack of skills necessary for daily living. This condition is now more commonly referred to as Intellectual Disability. The change in terminology reflects a broader understanding of the condition as not merely a deficit but as a spectrum of challenges that can be addressed with appropriate support and interventions. Intellectual disabilities can vary widely in their severity and in the impact they have on an individual's functioning.

Definition[edit | edit source]

Intellectual Disability (ID) is defined by the American Association on Intellectual and Developmental Disabilities (AAIDD) as a disability characterized by significant limitations in both intellectual functioning (reasoning, learning, problem-solving) and in adaptive behavior, which covers a range of everyday social and practical skills. This disability originates before the age of 18.

Causes[edit | edit source]

The causes of Intellectual Disability can be diverse and are often grouped into four categories: genetic conditions, problems during pregnancy, problems at birth, and health problems after birth. Genetic conditions, such as Down Syndrome, Fragile X Syndrome, and phenylketonuria (PKU), can lead to intellectual disabilities. Problems during pregnancy that affect brain development include alcohol or drug use, malnutrition, certain infections, or preeclampsia. Complications during birth, including preterm birth and oxygen deprivation, can also cause ID. After birth, conditions like whooping cough, measles, or meningitis, as well as severe malnutrition and exposure to toxic substances, can lead to intellectual disabilities.

Diagnosis[edit | edit source]

Diagnosis of Intellectual Disability involves a comprehensive evaluation that includes IQ testing and an assessment of adaptive behaviors. The Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria require a score approximately two standard deviations below the mean on standardized IQ tests, as well as significant limitations in adaptive behavior.

Management[edit | edit source]

Management of Intellectual Disability focuses on developing the individual's functional skills. Early intervention, educational programs, and family support play crucial roles in this process. Therapies such as speech therapy, occupational therapy, and physical therapy may be beneficial. In some cases, medication may be used to manage symptoms of associated conditions or behaviors that could hinder the individual's ability to participate in interventions.

Social and Legal Aspects[edit | edit source]

Societal attitudes towards Intellectual Disability have evolved significantly over time. There has been a shift towards more inclusive policies and practices that aim to integrate individuals with intellectual disabilities into all aspects of community life. Legal frameworks in many countries now recognize the rights of individuals with disabilities and mandate the provision of services and supports to enable their full participation in society.

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Contributors: Prab R. Tumpati, MD