Mobenakin

Mobenakin

Mobenakin is a pharmaceutical compound used primarily in the treatment of certain cardiovascular conditions. It is classified as a beta-blocker, which functions by blocking the effects of epinephrine (adrenaline) on the heart and blood vessels, thereby reducing heart rate, blood pressure, and strain on the heart.

Pharmacology

Mobenakin works by selectively inhibiting beta-1 adrenergic receptors in the heart. This action decreases the heart rate and contractility, leading to a reduction in cardiac output and blood pressure. Unlike non-selective beta-blockers, Mobenakin has a higher affinity for beta-1 receptors, which are predominantly found in cardiac tissue, thus minimizing the risk of bronchoconstriction in patients with respiratory conditions.

Indications

Mobenakin is indicated for the management of:

• Hypertension (high blood pressure)
• Angina pectoris (chest pain)
• Heart failure
• Arrhythmias (irregular heartbeats)

Contraindications

Mobenakin should not be used in patients with:

• Severe bradycardia (slow heart rate)
• Heart block greater than first degree
• Cardiogenic shock
• Decompensated heart failure

Side Effects

Common side effects of Mobenakin include:

• Fatigue
• Dizziness
• Cold extremities
• Bradycardia

Less common but serious side effects may include:

• Heart block
• Worsening of heart failure
• Bronchospasm

Dosage and Administration

Mobenakin is typically administered orally, with the dosage adjusted based on the patient's response and clinical condition. It is important to start with a low dose and titrate gradually to minimize the risk of adverse effects.

Mechanism of Action

Mobenakin's primary mechanism involves the competitive antagonism of catecholamines at beta-1 adrenergic receptors. This leads to decreased cyclic AMP levels, reduced calcium influx, and ultimately, decreased myocardial contractility and heart rate.

Research and Development

Mobenakin was developed in the late 20th century as part of a new generation of cardioselective beta-blockers. Ongoing research is focused on its potential benefits in reducing cardiovascular events in high-risk populations.

Also see

• Beta-blocker
• Hypertension
• Angina pectoris
• Heart failure
• Arrhythmia

Cardiovascular disease A-Z

Most common cardiac diseases

• Cardiac arrhythmia‎
• Cardiogenetic disorders‎
• Cardiomegaly‎
• Cardiomyopathy‎
• Cardiopulmonary resuscitation‎
• Chronic rheumatic heart diseases‎
• Congenital heart defects‎
• Heart neoplasia‎
• Ischemic heart diseases‎
• Pericardial disorders
• Syndromes affecting the heart‎
• Valvular heart disease‎

A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z

A

• Accelerated idioventricular rhythm
• Acute decompensated heart failure
• Arteriosclerotic heart disease
• Athletic heart syndrome
• Atrial flutter
• Atrioventricular fistula
• Cardiovascular disease in Australia
• Autoimmune heart disease

B

• Brown atrophy of the heart

C

• Ebb Cade
• Cardiac allograft vasculopathy
• Cardiac amyloidosis
• Cardiac asthma
• Cardiac tamponade
• Cardiogenic shock
• Cardiogeriatrics
• Cardiorenal syndrome
• Cardiotoxicity
• Carditis
• Coronary artery aneurysm
• Coronary artery anomaly
• Coronary artery disease
• Spontaneous coronary artery dissection
• Coronary artery ectasia
• Coronary occlusion
• Coronary steal
• Coronary thrombosis
• Coronary vasospasm
• Cœur en sabot
• Coxsackievirus-induced cardiomyopathy

D

• Duke Treadmill Score
• Duroziez's disease

E

• Eisenmenger's syndrome
• Embryocardia
• Endocardial fibroelastosis
• Eosinophilic myocarditis

H

• Heart attack
• Heart failure
• Heart failure with preserved ejection fraction
• Heart to Heart (1949 film)
• High-output heart failure
• Hyperdynamic precordium

A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z

I

• Idiopathic giant-cell myocarditis
• Interventricular dyssynchrony
• Intraventricular dyssynchrony
• Isolated atrial amyloidosis

K

• Keshan disease

L

• Loeffler endocarditis

M

• Mydicar
• Myocardial bridge
• Myocardial disarray
• Myocardial rupture
• Myocardial scarring
• Myocardial stunning
• Myocarditis

N

• Nonbacterial thrombotic endocarditis

O

• OLR1
• Ostial disease

P

• Papillary fibroelastoma
• Pathophysiology of heart failure
• Postpericardiotomy syndrome
• Pulmonary vein stenosis

R

• Right axis deviation
• Roemheld syndrome

S

• Saturated fat and cardiovascular disease
• SCAR-Fc
• Shone's syndrome
• Strain pattern
• Subacute bacterial endocarditis
• Sudden cardiac death of athletes

A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z

T

• Traumatic cardiac arrest

V

• Ventricular aneurysm
• Vibroacoustic disease
• Viral cardiomyopathy

W

• Waon therapy