Poorly differentiated thyroid cancer
Poorly differentiated thyroid carcinoma is malignant neoplasm of follicular cell origin showing intermediate histopathological patterns between differentiated and undifferentiated thyroid cancers.[1]
Histopathology[edit | edit source]
- Presence of small cells with round nuclei and scant cytoplasm with a diffuse solid pattern
- Round or oval nests (insulae) or in trabeculae.
- Solid growth and presence of microfollicles, some of which contain dense colloid.
- Extrathyroidal extension and blood vessel invasion
- Foci of necrosis,
- Larger than 5 cm in greatest diameter at diagnosis
Epidemiology[edit | edit source]
- PDTC affects predominantly females about 55 years of age
References[edit | edit source]
External links[edit | edit source]
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Contributors: Prab R. Tumpati, MD
