Sodium dodecyl sulfate

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Sodium dodecyl sulfate
Dodecylsulfate-3D

Sodium dodecyl sulfate (SDS), often referred to as lauryl sulfate, is an anionic surfactant commonly employed in a range of industrial and biological applications. Its primary function is to reduce the surface tension of aqueous solutions, making it invaluable in sectors like cosmetics, pharmaceuticals, and biochemistry.

Properties and Composition[edit | edit source]

SDS is predominantly a mixture of sodium alkyl sulfates. Its principal component is the lauryl group, which lends to its anionic nature. The surfactant nature of SDS allows it to lower the surface tension of water-based solutions, allowing them to wet surfaces more effectively.

Applications[edit | edit source]

Cosmetics and Personal Care[edit | edit source]

In the cosmetics industry, SDS is used as a detergent due to its capacity to emulsify fats and remove impurities from the skin and hair. Its presence can be found in a variety of products including:

  • Shampoos
  • Body washes
  • Toothpastes

Pharmaceuticals[edit | edit source]

In pharmaceutical formulations, SDS acts as a wetting agent, ensuring even dispersion of ingredients. Its surfactant properties aid in enhancing the solubility of certain drugs.

Research and Biochemistry[edit | edit source]

SDS has found a niche in protein biochemistry research. It plays a crucial role in:

  • SDS-PAGE (Polyacrylamide Gel Electrophoresis): A method used for separating proteins based on their molecular weight.
  • Denaturing proteins: SDS can bind to proteins and give them a negative charge, allowing researchers to study their properties in isolation.

Safety Considerations[edit | edit source]

While SDS is used in many consumer products, its concentration is typically kept low to avoid potential irritation to the skin and eyes. It's essential to handle SDS with care, especially in its concentrated form.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD