Lactitol
What is Lactitol?[edit | edit source]
What are the uses of this medicine?[edit | edit source]
- This medicine is indicated for chronic idiopathic constipation (CIC) in adults.
How does this medicine work?[edit | edit source]
- Lactitol exerts an osmotic effect, causing the influx of water into the small intestine leading to a laxative effect in the colon.
Who Should Not Use this medicine ?[edit | edit source]
This medicine cannot be used in patients with:
- known or suspected mechanical gastrointestinal obstruction
- galactosemia
What drug interactions can this medicine cause?[edit | edit source]
- PIZENSY may reduce the absorption of concomitantly administered oral medications.
- Administer oral medications at least 2 hours before or 2 hours after PIZENSY.
Is this medicine FDA approved?[edit | edit source]
- It was approved for use in the United States in 2020.
How should this medicine be used?[edit | edit source]
Recommended Dosage
- The recommended adult dosage of PIZENSY is 20 grams orally once daily, preferably with meals.
- Reduce the dosage to 10 grams once daily for persistent loose stools.
- Administer oral medications at least 2 hours before or 2 hours after PIZENSY.
Administration
PIZENSY Multi-dose bottle
- The multi-dose bottles are equipped with a measuring cap marked to contain 10 grams of powder when filled to the top of white section in cap.
- Pour the measured dose into an empty 8-ounce glass.
- Add 4 ounces to 8 ounces of water, juice or other common beverages (coffee, tea, soda) and stir to dissolve.
- Drink the entire contents of the glass.
PIZENSY Unit-dose packets
- The unit-dose packets contain 10 grams of PIZENSY each.
- Pour the contents of one or two unit-dose packets, as prescribed, into an empty 8-ounce glass.
- Add 4 ounces to 8 ounces of water, juice or other common beverages (coffee, tea, soda) to the glass containing the powder and stir thoroughly to dissolve.
- Drink the entire contents of the glass.
What are the dosage forms and brand names of this medicine?[edit | edit source]
This medicine is available in fallowing doasage form:
As Oral Solution:
- 280 grams of lactitol in multi-dose bottles
- 560 grams of lactitol in multi-dose bottles
- 10 grams of lactitol in unit-dose packets
This medicine is available in fallowing brand namesː
- PIZENSY
What side effects can this medication cause?[edit | edit source]
The most common side effects of this medicine include:
- upper respiratory tract infection
- flatulence
- diarrhea
- increased blood creatinine phosphokinase
- abdominal distention
- increased blood pressure
What special precautions should I follow?[edit | edit source]
What to do in case of emergency/overdose?[edit | edit source]
- In case of overdose, call the poison control helpline of your country. In the United States, call 1-800-222-1222.
- Overdose related information is also available online at poisonhelp.org/help.
- In the event that the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services. In the United States, call 911.
Can this medicine be used in pregnancy?[edit | edit source]
- Available data from case reports on lactitol use in pregnant women are insufficient to evaluate for any drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes.
Can this medicine be used in children?[edit | edit source]
- The safety and effectiveness of PIZENSY have not been established in pediatric patients.
What should I know about storage and disposal of this medication?[edit | edit source]
- Store at 20°C to 25°C (68° to 77°F). Excursions permitted between 15° to 30°C (59° to 86°F).
- Each bottle contains a white desiccant packet printed “Do Not Eat.”
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