Dentinogenesis imperfecta

From WikiMD's Wellnesspedia

Dentinogenesis imperfecta is a condition characterized by discolored (most often blue-gray or yellow-brown), translucent teeth. This condition is classified into three types based on the particular features present and the mode of inheritance.

Signs and Symptoms[edit | edit source]

The primary symptom of dentinogenesis imperfecta is the discoloration of the teeth, which can range from blue-gray to yellow-brown. The teeth are also often translucent. Other symptoms can include:

  • Teeth that are weaker than normal
  • Teeth that wear away quickly
  • Teeth that break easily

Causes[edit | edit source]

Dentinogenesis imperfecta is caused by mutations in the DSPP gene. This gene provides instructions for making two proteins, dentin sialoprotein and dentin phosphoprotein, which are involved in the formation of dentin, a hard, bone-like tissue that makes up most of the teeth. Mutations in the DSPP gene alter the structure of these proteins, disrupting the normal formation of dentin and leading to the signs and symptoms of dentinogenesis imperfecta.

Diagnosis[edit | edit source]

Diagnosis of dentinogenesis imperfecta is based on the clinical examination of the teeth. The diagnosis can be confirmed by genetic testing to identify mutations in the DSPP gene.

Treatment[edit | edit source]

Treatment for dentinogenesis imperfecta is aimed at protecting the teeth, improving the appearance of the teeth, and maintaining the health of the teeth and gums. This can include the use of crowns, veneers, bonding, and other dental procedures.

See Also[edit | edit source]

References[edit | edit source]


Dentinogenesis imperfecta Resources

Find a healthcare provider anywhere in the world quickly and easily!

Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.


Contributors: Prab R. Tumpati, MD