Flumethrin
Flumethrin is a pyrethroid insecticide that is primarily used in veterinary medicine to control parasites such as ticks and mites. It is a synthetic compound that is highly effective at low doses and has a broad spectrum of activity against a variety of pests.
Chemistry[edit | edit source]
Flumethrin is a complex organic compound with the chemical formula C28H22Cl2FNO3. It is a member of the pyrethroids, a class of synthetic compounds that mimic the insecticidal properties of the natural compound pyrethrin, which is derived from the flowers of plants in the chrysanthemum family.
Mode of Action[edit | edit source]
Flumethrin acts on the nervous system of insects, causing rapid paralysis and death. It binds to the voltage-gated sodium channels in nerve cell membranes, disrupting the normal function of the nervous system. This mode of action is similar to other pyrethroids and to the natural insecticide pyrethrin.
Uses[edit | edit source]
Flumethrin is primarily used in veterinary medicine to control external parasites on animals. It is effective against a wide range of pests, including ticks, mites, lice, and flies. It is often used in combination with other insecticides in products such as flea collars and spot-on treatments.
Safety[edit | edit source]
Like other pyrethroids, flumethrin is generally safe for use on animals but can be harmful or fatal if swallowed or absorbed through the skin. It is also highly toxic to fish and other aquatic organisms.
Environmental Impact[edit | edit source]
Flumethrin is not easily broken down in the environment and can persist in soil and water for long periods. This persistence, combined with its toxicity to non-target organisms, has raised concerns about its environmental impact.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD