GNA13
GNA13 is a protein that in humans is encoded by the GNA13 gene. It is a member of the G protein family, specifically the G12/13 subfamily. G proteins are involved in transmitting signals from a variety of stimuli outside a cell to its interior.
Function[edit | edit source]
The GNA13 protein is a guanine nucleotide-binding protein (G protein) which functions as a molecular switch inside cells. It is involved in regulating a variety of cellular processes including cell division, cell differentiation, and cell migration. GNA13 is particularly important in the regulation of angiogenesis and lymphangiogenesis, the formation of new blood vessels and lymphatic vessels, respectively.
Clinical significance[edit | edit source]
Mutations in the GNA13 gene have been associated with a variety of diseases. For example, it has been implicated in the development of cancer, particularly breast cancer and colorectal cancer. In addition, GNA13 has been linked to immune system disorders, such as rheumatoid arthritis and systemic lupus erythematosus.
Research[edit | edit source]
Research into the GNA13 gene and its associated protein is ongoing. Current areas of focus include understanding the precise role of GNA13 in cell signaling and investigating potential therapeutic applications for manipulating GNA13 activity in disease treatment.
See also[edit | edit source]
- G protein
- G12/13 subfamily
- Guanine nucleotide-binding protein
- Angiogenesis
- Lymphangiogenesis
- Cancer
- Breast cancer
- Colorectal cancer
- Immune system
- Rheumatoid arthritis
- Systemic lupus erythematosus
 | This medical article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
