Long QT syndrome
(Redirected from Long QT syndrome 4)
Long QT syndrome (LQTS) is a genetic disorder that affects the heart's electrical activity. It is characterized by a prolonged QT interval on an electrocardiogram (ECG), which can lead to arrhythmias, syncope, and sudden cardiac arrest.
Pathophysiology[edit | edit source]
Long QT syndrome is caused by mutations in genes that encode for ion channels in the heart. These ion channels are responsible for the flow of potassium, sodium, and calcium ions, which are crucial for the heart's electrical activity. The most commonly affected genes include KCNQ1, KCNH2, and SCN5A. Mutations in these genes can disrupt the normal flow of ions, leading to a prolonged QT interval.
Types[edit | edit source]
There are several types of Long QT syndrome, classified based on the specific gene mutation:
- LQT1: Caused by mutations in the KCNQ1 gene.
- LQT2: Caused by mutations in the KCNH2 gene.
- LQT3: Caused by mutations in the SCN5A gene.
Symptoms[edit | edit source]
Individuals with Long QT syndrome may experience:
Diagnosis[edit | edit source]
Diagnosis of Long QT syndrome typically involves:
- Electrocardiogram (ECG) to measure the QT interval.
- Genetic testing to identify specific mutations.
- Holter monitor to record heart activity over 24-48 hours.
- Exercise stress test to observe heart activity during physical exertion.
Treatment[edit | edit source]
Treatment options for Long QT syndrome include:
- Beta blockers to reduce the risk of arrhythmias.
- Implantable cardioverter-defibrillator (ICD) for individuals at high risk of sudden cardiac arrest.
- Lifestyle modifications such as avoiding strenuous exercise and certain medications that can prolong the QT interval.
Prognosis[edit | edit source]
With appropriate treatment and lifestyle modifications, individuals with Long QT syndrome can lead relatively normal lives. However, the risk of sudden cardiac arrest remains, particularly in untreated individuals.
Related Pages[edit | edit source]
Categories[edit | edit source]
Cardiovascular disease A-Z
Most common cardiac diseases
- Cardiac arrhythmia
- Cardiogenetic disorders
- Cardiomegaly
- Cardiomyopathy
- Cardiopulmonary resuscitation
- Chronic rheumatic heart diseases
- Congenital heart defects
- Heart neoplasia
- Ischemic heart diseases
- Pericardial disorders
- Syndromes affecting the heart
- Valvular heart disease
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
A[edit source]
- Accelerated idioventricular rhythm
- Acute decompensated heart failure
- Arteriosclerotic heart disease
- Athletic heart syndrome
- Atrial flutter
- Atrioventricular fistula
- Cardiovascular disease in Australia
- Autoimmune heart disease
B[edit source]
C[edit source]
- Ebb Cade
- Cardiac allograft vasculopathy
- Cardiac amyloidosis
- Cardiac asthma
- Cardiac tamponade
- Cardiogenic shock
- Cardiogeriatrics
- Cardiorenal syndrome
- Cardiotoxicity
- Carditis
- Coronary artery aneurysm
- Coronary artery anomaly
- Coronary artery disease
- Spontaneous coronary artery dissection
- Coronary artery ectasia
- Coronary occlusion
- Coronary steal
- Coronary thrombosis
- Coronary vasospasm
- Cœur en sabot
- Coxsackievirus-induced cardiomyopathy
D[edit source]
E[edit source]
H[edit source]
- Heart attack
- Heart failure
- Heart failure with preserved ejection fraction
- Heart to Heart (1949 film)
- High-output heart failure
- Hyperdynamic precordium
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
I[edit source]
- Idiopathic giant-cell myocarditis
- Interventricular dyssynchrony
- Intraventricular dyssynchrony
- Isolated atrial amyloidosis
K[edit source]
L[edit source]
M[edit source]
- Mydicar
- Myocardial bridge
- Myocardial disarray
- Myocardial rupture
- Myocardial scarring
- Myocardial stunning
- Myocarditis
N[edit source]
O[edit source]
P[edit source]
- Papillary fibroelastoma
- Pathophysiology of heart failure
- Postpericardiotomy syndrome
- Pulmonary vein stenosis
R[edit source]
S[edit source]
- Saturated fat and cardiovascular disease
- SCAR-Fc
- Shone's syndrome
- Strain pattern
- Subacute bacterial endocarditis
- Sudden cardiac death of athletes
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
T[edit source]
V[edit source]
W[edit source]
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Contributors: Prab R. Tumpati, MD