Penile agenesis
Penile agenesis is a rare birth defect in males where the penis is absent due to its failure to develop. This condition is also known as aphallia. It is often associated with other anomalies such as urogenital and anorectal malformations.
Causes[edit | edit source]
The exact cause of penile agenesis is unknown. However, it is believed to be due to a disruption in the development of the genital tubercle during the early stages of embryogenesis. This disruption can be caused by genetic mutations or environmental factors.
Diagnosis[edit | edit source]
Diagnosis of penile agenesis is usually made at birth due to the obvious absence of the penis. Further diagnostic tests such as ultrasound and magnetic resonance imaging (MRI) may be used to identify associated anomalies.
Treatment[edit | edit source]
Treatment of penile agenesis is complex and depends on the presence of associated anomalies. It often involves multiple surgeries to construct a functional and cosmetically acceptable phallus. Gender reassignment to female is also an option, especially in cases where the child has a normal female karyotype.
Prognosis[edit | edit source]
The prognosis for individuals with penile agenesis varies depending on the presence and severity of associated anomalies. With appropriate treatment, most individuals can lead a normal life.
See also[edit | edit source]
| Penile agenesis Resources | |
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References[edit | edit source]
External links[edit | edit source]
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Contributors: Prab R. Tumpati, MD
