A-955,840
A-955,840
A-955,840 is a chemical compound that has been studied for its potential use in medical applications, particularly in the field of neuroscience. It is known for its role as a selective antagonist of the α7 nicotinic acetylcholine receptor (nAChR), which is a type of receptor found in the central nervous system.
Chemical Properties[edit | edit source]
A-955,840 is a synthetic compound with a specific molecular structure that allows it to interact with the α7 nicotinic acetylcholine receptor. The chemical formula and molecular weight of A-955,840 are important for understanding its pharmacokinetics and pharmacodynamics.
Mechanism of Action[edit | edit source]
A-955,840 functions as an antagonist at the α7 nicotinic acetylcholine receptor. This receptor is a ligand-gated ion channel that, when activated by its natural ligand acetylcholine, allows the flow of ions such as calcium and sodium into the neuron. By blocking this receptor, A-955,840 can modulate neuronal signaling and has been studied for its effects on cognitive function and neuroprotection.
Potential Therapeutic Applications[edit | edit source]
Research into A-955,840 has focused on its potential use in treating conditions such as schizophrenia, Alzheimer's disease, and other cognitive disorders. The α7 nicotinic acetylcholine receptor is implicated in various neurological processes, and modulation of this receptor could have therapeutic benefits.
Research and Development[edit | edit source]
Studies involving A-955,840 have been conducted to evaluate its efficacy and safety in preclinical and clinical settings. These studies aim to determine the optimal dosing, potential side effects, and therapeutic window of the compound.
Safety and Side Effects[edit | edit source]
As with any pharmacological agent, understanding the safety profile of A-955,840 is crucial. Research has been conducted to assess its potential side effects, which may include impacts on cardiovascular function, gastrointestinal disturbances, and central nervous system effects.
Also see[edit | edit source]
- Nicotinic acetylcholine receptor
- Cognitive enhancers
- Neuropharmacology
- Schizophrenia treatment
- Alzheimer's disease research
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