Ancylostomiasis

A parasitic disease caused by hookworms

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Ancylostomiasis is a parasitic infection caused by hookworms, primarily affecting the small intestine. The most common species responsible for this condition are Ancylostoma duodenale and Necator americanus. These parasites are prevalent in tropical and subtropical regions, where they thrive in warm, moist environments.

Pathophysiology

Hookworms are transmitted through contact with contaminated soil. The larvae penetrate the skin, usually through the feet, and migrate through the bloodstream to the lungs. From the lungs, they ascend the trachea and are swallowed, eventually reaching the small intestine where they mature into adult worms. The adult worms attach to the intestinal wall, feeding on blood and causing significant blood loss.

Symptoms

The clinical manifestations of ancylostomiasis can vary depending on the intensity of the infection. Common symptoms include:

• Iron deficiency anemia due to blood loss
• Fatigue and weakness
• Abdominal pain
• Diarrhea
• Weight loss
• Itchy rash at the site of larval penetration, known as "ground itch"

Diagnosis

Diagnosis of ancylostomiasis is typically made through the identification of hookworm eggs in a stool sample. Microscopic examination is used to detect the characteristic eggs, which are oval and have a thin shell.

Treatment

The treatment of choice for ancylostomiasis is the administration of anthelmintic medications such as albendazole or mebendazole. These drugs are effective in eradicating the adult worms from the intestine. In addition to anthelmintic therapy, iron supplementation may be necessary to address anemia.

Prevention

Preventive measures for ancylostomiasis focus on improving sanitation and reducing soil contamination. Key strategies include:

• Wearing shoes to prevent skin penetration by larvae
• Proper disposal of human feces
• Health education to raise awareness about the transmission and prevention of hookworm infections

Epidemiology

Ancylostomiasis is a significant public health concern in many developing countries, particularly in areas with poor sanitation. It is estimated that over 500 million people worldwide are infected with hookworms, with the highest prevalence in sub-Saharan Africa, Southeast Asia, and Latin America.

Related pages

• Helminthiasis
• Parasitic disease
• Soil-transmitted helminthiasis