Intravascular papillary endothelial hyperplasia

Intravascular papillary endothelial hyperplasia (IPEH), also known as Masson's tumor, is a benign vascular lesion characterized by excessive proliferation of endothelial cells. It is a rare condition that can occur anywhere in the body, but is most commonly found in the skin and subcutaneous tissues.

Etiology

The exact cause of IPEH is unknown. However, it is believed to be a reactive process that occurs in response to vascular injury or thrombosis. Some studies suggest that it may be associated with certain conditions such as hemangioma, venous malformation, and pyogenic granuloma.

Clinical Presentation

Patients with IPEH typically present with a slow-growing, painless mass. The size of the lesion can vary, but it is usually less than 2 cm in diameter. The skin over the lesion may appear normal or may show signs of erythema or ulceration. In rare cases, patients may experience pain or tenderness.

Diagnosis

The diagnosis of IPEH is usually made based on histopathological examination. The lesion is characterized by the presence of papillary structures with a central hyaline core and an outer layer of proliferating endothelial cells. Immunohistochemical staining can be used to confirm the diagnosis.

Treatment

The treatment of choice for IPEH is surgical excision. The prognosis is generally good, with a low risk of recurrence.

Histopathology Images

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See Also

• Vascular lesion
• Hemangioma
• Venous malformation
• Pyogenic granuloma

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