Myositis

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Obesity, Sleep & Internal medicine
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Myositis
File:IBM rimmed vacuoles HE x200.jpg Rimmed vacuoles in inclusion body myositis
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Muscle weakness, muscle pain, fatigue
Complications	Difficulty swallowing, respiratory issues
Onset	Gradual
Duration	Long-term
Types	Polymyositis, Dermatomyositis, Inclusion body myositis
Causes	Autoimmune, infections, medications
Risks	Genetic predisposition, age, gender
Diagnosis	Muscle biopsy, Blood test for creatine kinase, Electromyography
Differential diagnosis	Muscular dystrophy, Amyotrophic lateral sclerosis, Multiple sclerosis
Prevention	N/A
Treatment	Corticosteroids, Immunosuppressants, Physical therapy
Medication	Prednisone, Methotrexate, Azathioprine
Prognosis	Variable, depends on type and response to treatment
Frequency	Rare
Deaths	N/A

Myositis

File:Inclusion body myositis MRI.jpg

Inclusion body myositis MRI

Myositis is inflammation or swelling of the muscles. Injury, medicines, infection, or an immune disorder can lead to myositis. It is a documented side effect of the lipid-lowering drugs statins and fibrates.

Types

Types of myositis include:

• myositis ossificans
• (idiopathic) inflammatory myopathies

dermatomyositis * juvenile dermatomyositis polymyositis inclusion body myositis benign acute childhood myositis Statin-associated autoimmune myopathy

• pyomyositis

Diagnosis

Elevation of creatine kinase in blood is indicative of myositis.

Treatment

Polymyositis and dermatomyositis are first treated with high doses of corticosteroids.

See also

• myopathy (muscle disease)
• myalgia (muscle pain)
• Masticatory muscle myositis (a disease in dogs)
• perimyositis

External links

• Myositis: NIH