Uterine Carcinosarcoma

Carcinosarcoma
	Carcinosarcoma of the endometrium - annotated.jpg
	Micrograph of a carcinosarcoma of the endometrium. H&E stain. ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ;

Other Names[edit]

Malignant mixed müllerian tumor of corpus uteri; Mixed müllerian cancer of corpus uteri; Carcinosarcoma of the corpus uteri; Malignant mixed Müllerian tumor of the corpus uteri

Pathophysiology[edit]

Carcinosarcoma of the corpus uteri is a rare, malignant, mixed epithelial and mesenchymal tumor of the uterine body composed of high-grade carcinomatous and sarcomatous elements.

Clinical presentation[edit]

It may present with vaginal bleeding, abnormal vaginal discharge, abdominal pain and/or pelvic mass, with a polypoid tumor sometimes protruding through the cervical canal.

Risk factors[edit]

Association with Tamoxifen therapy, long-term unopposed estrogen use and previous pelvic radiotherapy has been reported.

External links[edit]

Carcinosarcoma entry in the public domain NCI Dictionary of Cancer Terms

File:PD-icon.svg This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".