Wilm's tumor

Wilm's Tumor (also known as Nephroblastoma) is a rare kidney cancer that primarily affects children. The cause is unknown, but it is most commonly diagnosed in children aged 3 to 4 years. It is named after Dr. Max Wilms, the German surgeon who first described it in 1899.

Symptoms and Signs

The most common symptom of Wilm's tumor is a swollen abdomen, which is usually painless. Other symptoms may include blood in the urine, high blood pressure, fever, loss of appetite, and general malaise.

Causes

The exact cause of Wilm's tumor is unknown, but it is thought to be related to certain genetic mutations. Some children with Wilm's tumor also have other birth defects, suggesting a possible genetic component.

Diagnosis

Diagnosis of Wilm's tumor typically involves a physical examination, blood and urine tests, and imaging studies such as ultrasound, CT scan, or MRI. A biopsy may also be performed to confirm the diagnosis.

Treatment

Treatment for Wilm's tumor usually involves surgery to remove the tumor, followed by chemotherapy and/or radiation therapy. The prognosis is generally good, with a survival rate of over 90% in children who are diagnosed and treated early.

See Also

• Kidney cancer
• Pediatric oncology
• Genetic mutation

References

Wilm's tumor Resources
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