Fiasp
Fiasp is a rapid-acting insulin analog used to improve blood sugar control in adults and children with diabetes mellitus. It is a formulation of insulin aspart that includes additional excipients to accelerate its absorption and onset of action.
Composition[edit | edit source]
Fiasp contains the active ingredient insulin aspart, which is a rapid-acting human insulin analog. The formulation also includes nicotinamide (vitamin B3) to increase the speed of absorption, and arginine, an amino acid, to stabilize the insulin molecule.
Mechanism of Action[edit | edit source]
Fiasp works by mimicking the body's natural insulin response to meals. It helps to lower blood glucose levels by facilitating the uptake of glucose into cells, particularly in the liver, muscle, and fat tissue. This rapid-acting insulin analog begins to work within minutes of injection, making it suitable for use at mealtime.
Indications[edit | edit source]
Fiasp is indicated for the treatment of type 1 diabetes mellitus and type 2 diabetes mellitus in adults and children. It is typically administered subcutaneously before meals or within 20 minutes after starting a meal.
Administration[edit | edit source]
Fiasp is available in multiple forms, including:
- Vials
- Prefilled pens
- Cartridges for use in insulin pumps
The dosage and timing of Fiasp administration should be individualized based on the patient's needs, blood glucose monitoring results, and glycemic control goals.
Side Effects[edit | edit source]
Common side effects of Fiasp include:
- Hypoglycemia
- Injection site reactions
- Allergic reactions
- Weight gain
Patients should be monitored for signs of hypoglycemia and other adverse effects, and adjustments to the dosage may be necessary.
Storage[edit | edit source]
Fiasp should be stored in a refrigerator at 2°C to 8°C (36°F to 46°F) until the expiration date. Once in use, it can be kept at room temperature (below 30°C or 86°F) for up to 28 days.
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Contributors: Prab R. Tumpati, MD