Walthard cell rest

From WikiMD's Wellnesspedia

Micrograph of a cystic Walthard cell rest (lower right of image) within the connective tissue of a Fallopian tube (tubal epithelium - upper left of image). H&E stain.

Walthard cell rests; sometimes called Walthard cell nests, are a benign cluster of epithelial cells most commonly found in the connective tissue of the Fallopian tubes, but also seen in the mesovarium, mesosalpinx and ovarian hilus.

Appearance[edit | edit source]

High magnification micrograph of a cystic Walthard cell rest showing the characteristic coffee bean-shaped nuclei. H&E stain.

They appear as white/yellow cysts or nodules that can reach a size of 2 millimeters. They typically have elliptical nuclei with a long groove (along the major axis) - so called - "coffee bean" nuclei.

Pathology[edit | edit source]

It has been suggested that these cell rests are the histogenetic origins of Brenner tumors, due to the histological similarity of the epithelium of Walthard cell rests and Brenner tumors to the urothelium of the lower urinary tract. Also, it has been proposed that Brenner tumors and Walthard cell rests signify urothelial differentiation within the female genital tract.

Eponym[edit | edit source]

They are named after Swiss gynecologist Max Walthard (1867–1933), who provided a comprehensive description of them in 1903.

Additional images[edit | edit source]

References[edit | edit source]

Portions of content adapted from Wikipedia's article on Walthard cell rest which is released under the CC BY-SA 3.0.

Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.


Contributors: Prab R. Tumpati, MD