Antiarrhythmic
Anti-arrythmic, as the name suggests, is a drug used to treat an abnormal heart rhythm, also called arrythmia. Examples of drugs considered as antiarrhytmic include the following:
- Betablockers such as metoprololol (lopressor, topral)
- Amiodarone (Cordarone, Pacerone)
- flecainide (Tambocor)
- ibutilide (Corvert), which can only be given through IV.
- lidocaine (Xylocaine), which can only be given through IV.
- procainamide (Procan, Procanbid)
- propafenone (Rythmol)
- quinidine (many brand names)
- tocainide (Tonocarid)
Classes of antiarrythmic drugs[edit | edit source]
The five main classes in the Vaughan Williams classification of antiarrhythmic agents are:
- Class I agents interfere with the sodium (Na+) channel.
- Class II agents are anti-sympathetic nervous system agents. Most agents in this class are beta blockers.
- Class III agents affect potassium (K+) efflux.
- Class IV agents affect calcium channels and the AV node.
- Class V agents work by other or unknown mechanisms.
List of antiarrhythmic agents:
- Amiodarone
- Disopyramide
- Dofetilide
- Dronedarone
- Flecainide
- Ivabradine
- Mexiletine
- Procainamide
- Propafenone
- Quinidine
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