Gallium 68 PSMA-11

What Is Gallium 68 PSMA-11?[edit | edit source]

Gallium 68 PSMA-11 Injection is a radioactive diagnostic agent indicated for positron emission tomography (PET).

Ga 68 PSMA-11 is indicated for patients with suspected prostate cancer metastasis (when cancer cells spread from the place where they first formed to another part of the body) who are potentially curable by surgery or radiation therapy.
Ga 68 PSMA-11 is also indicated for patients with suspected prostate cancer recurrence based on elevated serum prostate-specific antigen (PSA) levels.
Ga 68 PSMA-11 is a radioactive diagnostic agent that is administered in the form of an intravenous injection.

Once administered via injection, Ga 68 PSMA-11 binds to PSMA, which is an important pharmacologic target for prostate cancer imaging because prostate cancer cells usually contain elevated levels of the antigen.
As a radioactive drug that emits positrons, Ga 68 PSMA-11 can be imaged by PET to indicate the presence of PSMA-positive prostate cancer lesions in the tissues of the body.

In adults, the recommended amount of radioactivity to be administered for PET is 111 MBq to 259 MBq (3 mCi to 7 mCi) administered as an intravenous bolus injection.
A diuretic expected to act within the uptake time period may be administered at the time of radiotracer injection.
Initiate imaging 50 to 100 minutes after administration.
The patient should void immediately prior to initiation of imaging.
Scan should begin caudally and proceed cranially.

This medicine is available in fallowing doasage form:

This medicine is supplied as injections : supplied as a clear, colorless solution in a 30 mL multiple-dose vial containing 18.5 MBq/mL to 185 MBq/mL (0.5 mCi/mL to 5 mCi/mL) of Ga 68 PSMA-11 at calibration time.

This medicine is available in fallowing brand namesː

Common possible side effects of this medicine include:

Image interpretation errors can occur with Ga 68 PSMA-11 PET.
Ensure safe handling to protect patients and health care workers from unintentional radiation exposure.

In the event of an overdose of Ga 68 PSMA-11 Injection, reduce the dose to the patient by increasing the elimination of the drug from the body using hydration and frequent bladder voiding.
A diuretic might also be considered.

Store Ga 68 PSMA-11 Injection upright in a lead shielded container at 25°C (77°F); excursions are permitted from 15°C to 30°C (59°F to 86°F).
Store Ga 68 PSMA-11 Injection within the original container in radiation shielding.

Gallium 68 PSMA-11 Resources
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