Gallium 68 PSMA-11

From WikiMD's Wellness Encyclopedia

What Is Gallium 68 PSMA-11?[edit | edit source]

What are the uses of this medicine?[edit | edit source]

  • Ga 68 PSMA-11 is indicated for patients with suspected prostate cancer metastasis (when cancer cells spread from the place where they first formed to another part of the body) who are potentially curable by surgery or radiation therapy.
  • Ga 68 PSMA-11 is also indicated for patients with suspected prostate cancer recurrence based on elevated serum prostate-specific antigen (PSA) levels.
  • Ga 68 PSMA-11 is a radioactive diagnostic agent that is administered in the form of an intravenous injection.

How does this medicine work?[edit | edit source]

  • Once administered via injection, Ga 68 PSMA-11 binds to PSMA, which is an important pharmacologic target for prostate cancer imaging because prostate cancer cells usually contain elevated levels of the antigen.
  • As a radioactive drug that emits positrons, Ga 68 PSMA-11 can be imaged by PET to indicate the presence of PSMA-positive prostate cancer lesions in the tissues of the body.

Who Should Not Use this medicine ?[edit | edit source]

  • Ga 68 PSMA-11 have no usage limitations

Is this medicine FDA approved?[edit | edit source]

  • It was approved for use in the United States in 2020.

How should this medicine be used?[edit | edit source]

  • In adults, the recommended amount of radioactivity to be administered for PET is 111 MBq to 259 MBq (3 mCi to 7 mCi) administered as an intravenous bolus injection.
  • A diuretic expected to act within the uptake time period may be administered at the time of radiotracer injection.
  • Initiate imaging 50 to 100 minutes after administration.
  • The patient should void immediately prior to initiation of imaging.
  • Scan should begin caudally and proceed cranially.

What are the dosage forms and brand names of this medicine?[edit | edit source]

This medicine is available in fallowing doasage form:

  • This medicine is supplied as injections : supplied as a clear, colorless solution in a 30 mL multiple-dose vial containing 18.5 MBq/mL to 185 MBq/mL (0.5 mCi/mL to 5 mCi/mL) of Ga 68 PSMA-11 at calibration time.

This medicine is available in fallowing brand namesː

  • Gallium 68 PSMA-11

What side effects can this medication cause?[edit | edit source]

Common possible side effects of this medicine include:

  • nausea
  • diarrhea
  • dizziness

What special precautions should I follow?[edit | edit source]

  • Image interpretation errors can occur with Ga 68 PSMA-11 PET.
  • Ensure safe handling to protect patients and health care workers from unintentional radiation exposure.

What to do in case of emergency/overdose?[edit | edit source]

  • In the event of an overdose of Ga 68 PSMA-11 Injection, reduce the dose to the patient by increasing the elimination of the drug from the body using hydration and frequent bladder voiding.
  • A diuretic might also be considered.

Can this medicine be used in pregnancy?[edit | edit source]

  • Ga 68 PSMA-11 Injection is not indicated for use in females.
  • There are no available data with Ga 68 PSMA-11 Injection use in pregnant women.

Can this medicine be used in children?[edit | edit source]

  • Ga 68 PSMA-11 Injection is not indicated for use in the pediatric population.

What should I know about storage and disposal of this medication?[edit | edit source]

  • Store Ga 68 PSMA-11 Injection upright in a lead shielded container at 25°C (77°F); excursions are permitted from 15°C to 30°C (59°F to 86°F).
  • Store Ga 68 PSMA-11 Injection within the original container in radiation shielding.


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