Kwashiorkor

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Kwashiorkor
File:Starved girl.jpg
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Edema, irritability, anorexia, ulcerating dermatoses, enlarged liver
Complications	Infection, shock, coma
Onset	Typically after weaning
Duration	Variable, depending on treatment
Types	N/A
Causes	Protein deficiency
Risks	Malnutrition, poverty, famine
Diagnosis	Clinical diagnosis, blood test
Differential diagnosis	Marasmus, anemia, liver disease
Prevention	Adequate dietary protein intake
Treatment	Nutritional rehabilitation, dietary supplements
Medication	N/A
Prognosis	Good with treatment, poor without
Frequency	Common in areas of famine and poverty
Deaths	N/A

Kwashiorkor is a severe form of malnutrition that primarily affects children living in regions where there is a shortage of quality food rich in protein. The condition occurs when a child's diet lacks adequate sources of protein, even though the overall calorie intake may be sufficient. Kwashiorkor is more common in areas of drought and famine, where access to balanced meals is limited.

Etiology

Kwashiorkor is caused by inadequate protein intake, often coupled with other micronutrient deficiencies. This condition is most prevalent in regions of the world where there is a scarcity of high-protein food, such as regions experiencing famine or areas where the staple diet is high in carbohydrates and low in protein.

File:Kwashiorkor 6180.jpg

Kwashiorkor 6180

Clinical Presentation

Children with kwashiorkor typically exhibit swollen and distended bellies due to fluid retention (edema), a condition known as ascites. Other symptoms may include muscle wasting, skin and hair changes (like lighter hair color and flaky or rashy skin), lethargy, and a failure to grow or gain weight.

Diagnosis

The diagnosis of kwashiorkor is primarily clinical, based on the presence of edema, growth failure, changes in skin and hair, and a history of inadequate protein intake. Laboratory tests may show low levels of serum proteins, particularly albumin, but these tests are not necessary for the diagnosis.

Treatment

The management of kwashiorkor involves the gradual introduction of a balanced diet, starting with fluids and gradually introducing higher-protein foods. During the initial phase, care must be taken to avoid refeeding syndrome, a potentially fatal condition that can occur when malnourished individuals are fed too quickly. Micronutrient supplements and medications may be used to treat any accompanying conditions or deficiencies.

Prognosis

With timely and appropriate treatment, the prognosis for children with kwashiorkor is generally good. However, some children may experience long-term complications, such as stunted growth and developmental delays, if treatment is not received promptly.

Prevention

Prevention of kwashiorkor involves ensuring that children have access to a balanced diet that includes sufficient protein. This often requires efforts at a community or national level to address the underlying issues of food security and poverty. Education about the importance of a balanced diet can also play a significant role.

See Also

• Protein-energy malnutrition
• Malnutrition
• Marasmus
• Micronutrient deficiency