Clarke Error Grid

Clarke Error Grid is a graphical method used in the field of diabetes management to evaluate the clinical accuracy of blood glucose monitoring systems. It was developed by Dr. William Clarke and his colleagues in the 1980s. The grid is divided into five zones (A, B, C, D, and E) that represent different levels of clinical accuracy and potential risk for the patient.

Overview

The Clarke Error Grid is a two-dimensional plot with the reference blood glucose measurement on the x-axis and the corresponding measurement from the blood glucose monitoring system on the y-axis. Each point on the plot represents a pair of measurements. The grid is divided into five zones:

• Zone A: The values from the monitoring system are within 20% of the reference value, which is considered clinically accurate.
• Zone B: The values from the monitoring system are outside of 20% of the reference value, but would not lead to inappropriate treatment.
• Zone C: The values from the monitoring system would lead to unnecessary treatment.
• Zone D: The values from the monitoring system would indicate a false sense of normoglycemia and delay treatment.
• Zone E: The values from the monitoring system are opposite to the reference value and could lead to dangerous treatment decisions.

File:Clarke Error Grid.png

Clarke Error Grid

Clinical Significance

The Clarke Error Grid is widely used in clinical studies to evaluate the performance of blood glucose monitoring systems. It provides a visual representation of the clinical accuracy of a system and the potential risk for the patient. The grid is particularly useful for comparing the performance of different systems and for assessing improvements in system accuracy over time.

See Also

• Blood glucose monitoring
• Diabetes management
• Continuous glucose monitor

References

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