COPD

Chronic obstructive pulmonary disease (COPD) is a complex lung condition characterized by chronic inflammation and airflow obstruction or limitation. This condition has several alternative names including chronic obstructive airway disease and chronic obstructive lung disease.

Copd versus healthy lung

BPCO 2010 Side

X-ray of COPD exacerbation - anteroposterior view

Definition

COPD encompasses a range of lung diseases that result in swelling of the airways. The most prevalent forms of this condition are:

• emphysema
• chronic bronchitis
• bronchiectasis

Causes, Incidence, and Risk Factors

Tobacco smoking remains the primary cause of COPD. Between 15% and 20% of long-term smokers are likely to develop this condition. Continuous exposure to tobacco results in persistent inflammation within the lungs and destruction of air sacs. Notably, in rare circumstances, an enzyme deficiency known as alpha-1 anti-trypsin deficiency can induce emphysema even in non-smokers.

Other associated risk factors include:

• Exposure to secondhand smoke
• Male gender
• Residing or working in a polluted environment

Symptoms and Diagnosis

Symptoms of COPD

Individuals suffering from COPD may exhibit:

• Persistent shortness of breath (dyspnea)
• Wheezing
• Reduced exercise tolerance
• Cough, which may or may not be accompanied by phlegm

Two Conditions of COPD

Upon examination, one might observe increased breathing effort, nasal flaring during inhalation, and pursed-lip breathing during exhalation. Flares of the disease might display intercostal retractions and the engagement of accessory breathing muscles.

Diagnostic tools include:

• Chest X-rays displaying lung hyperinflation
• Chest CT scans revealing emphysema
• Arterial blood gas tests indicating hypoxemia or respiratory acidosis
• Pulmonary function tests showing reduced airflow rates and lung over-expansion

Treatment

Addressing COPD often involves the use of inhalers that dilate the airways (bronchodilators) and sometimes theophylline. It is imperative for patients to abstain from smoking. In specific cases, inhaled steroids combat lung inflammation, and during severe episodes, oral or intravenous steroids might be administered.

Additional treatments include:

• Antibiotics during symptom flare-ups
• Chronic, low-flow oxygen
• Non-invasive ventilation or intubation
• Surgical removal of affected lung portions
• Lung rehabilitation programs
• Lung transplantation in extreme cases

Support Groups

Patients can often alleviate the stress of their illness by participating in support groups where experiences and concerns are shared.

Prognosis

COPD is a long-term illness and can deteriorate if tobacco usage persists.

Complications

Potential complications encompass:

• Right-sided heart failure or cor pulmonale
• Arrhythmias
• Dependency on mechanical ventilation or oxygen therapy
• Pneumothorax
• Pneumonia

In case of sudden shortness of breath or complication emergence, seek immediate medical attention.

Prevention

Preventing COPD largely hinges on avoiding smoking. Early diagnosis and treatment of small airway disease, along with ceasing tobacco usage, can deter disease progression.

COPD Resources
Latest articles Most recent articles Ongoing trials	Wikipedia