Mycoplasma

Mycoplasma is a genus of bacteria that lack a cell wall, making them naturally resistant to many common antibiotics such as penicillin or other beta-lactam antibiotics that target cell wall synthesis.

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M. haemofelis IP2011

Characteristics

Mycoplasma_felis

The absence of a cell wall gives mycoplasmas the flexibility to change shape and size, a trait that makes them difficult to identify and control. Additionally, this property allows them to survive and proliferate in a variety of environmental conditions.

Disease Involvement

Various species of Mycoplasma are pathogenic in humans. Most notably, Mycoplasma pneumoniae is a common cause of community-acquired pneumonia, while Mycoplasma genitalium is associated with sexually transmitted infections.

Diagnosis

Diagnosis of mycoplasma infections typically involves polymerase chain reaction (PCR) testing, culture, or serologic testing. These tests can identify the specific species responsible for infection.

Treatment

Since mycoplasmas are resistant to antibiotics that target cell wall synthesis, treatment usually involves antibiotics such as macrolides, tetracyclines, or fluoroquinolones. Additionally, symptomatic management may be necessary depending on the severity of the infection.

See Also

• Pneumonia
• Sexually transmitted infections

References

Mycoplasma Resources
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