Flortaucipir F18
What is Flortaucipir F18?[edit | edit source]
Flortaucipir F18s a radioactive drug.
What are the uses of this medicine?[edit | edit source]
- It is indicated for use with positron emission tomography (PET) imaging of the brain in adult patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD).
How does this medicine work?[edit | edit source]
- Tau protein misfolding is responsible for the developemnt of alzerimers disease.
- This drug acts by binding to the areads of the brian where there are misfolded Tau protein then, The brain can then be imaged with a PET scan to help identify the presence of tau pathology
Who Should Not Use this medicine?[edit | edit source]
There are no contraindications
Is this medicine FDA approved?[edit | edit source]
The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication.
How should this medicine be used?[edit | edit source]
- Flortaucipir F18 is a radioactive drug.
- Only authorized persons qualified by training and experience should receive, use, and administer it.
- Handle TAUVID with appropriate safety measures to minimize radiation exposure during administration
- Use waterproof gloves and effective shielding, including syringe shields, when preparing and handling TAUVID.
What are the dosage forms and brand names of this medicine?[edit | edit source]
- TAUVID is the brand name
- The recommended amount of radioactivity to be administered for PET imaging is 370 MBq (10 mCi), administered as an intravenous bolus injection in a total volume of 10 mL or less.
What side effects can this medication cause?[edit | edit source]
- Headache
- Inscision site pain
- Increased blood pressure
What special precautions should I follow?[edit | edit source]
- Ensure safe handling and preparation procedures to protect patients and health care workers from unintentional radiation exposure
- TAUVID is not indicated for detection of chronic traumatic encephalopathy[CTE]
- There are chances for a false negative results with this drug , Consider additional evaluation to confirm the absence of AD pathology in patients with a negative TAUVID scan.
What to do in case of emergency/overdose?[edit | edit source]
- In case of overdose, call the poison control helpline of your country. In the United States, call 1-800-222-1222.
- Overdose related information is also available online at poisonhelp.org/help.
- In the event that the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services. In the United States, call 911.
Can this medicine be used in pregnancy?[edit | edit source]
- No, radioactive elements can cause damage to fetus
- TAUVID is not likely to be used in females of reproductive age.
Can this medicine be used in children?[edit | edit source]
The safety and effectiveness of TAUVID in pediatric patients have not been established.
What should I know about storage and disposal of this medication?[edit | edit source]
- Store TAUVID at 25°C (77°F)
- TAUVID does not contain a preservative
- Store TAUVID upright in a shielding container
- The expiration date and time are provided on the container label.
- Use TAUVID within the labeled expiration.
Handling This preparation is approved for use by persons under license by the Nuclear Regulatory Commission or the relevant regulatory authority of an Agreement State.
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