Weber's syndrome
(Redirected from Midbrain stroke syndromes)
| Weber's syndrome | |
|---|---|
| |
| Synonyms | Superior alternating hemiplegia |
| Pronounce | |
| Field | N/A |
| Symptoms | |
| Complications | |
| Onset | |
| Duration | |
| Types | |
| Causes | |
| Risks | |
| Diagnosis | |
| Differential diagnosis | |
| Prevention | |
| Treatment | anything which can decrease the stroke's effect |
| Medication | |
| Prognosis | |
| Frequency | |
| Deaths | |
Weber's syndrome, also known as superior alternating hemiplegia, is a form of stroke characterized by the presence of an ipsilateral oculomotor nerve palsy and contralateral hemiparesis or hemiplegia. It is caused by midbrain infarction as a result of occlusion of the paramedian branches of the posterior cerebral artery or of basilar bifurcation perforating arteries.[1]
Cause[edit | edit source]
This lesion is usually unilateral and affects several structures in the midbrain including:
| Structure damaged | Effect |
|---|---|
| substantia nigra | contralateral parkinsonism because its dopaminergic projections to the basal ganglia innervate the ipsilateral hemisphere motor field, leading to a movement disorder of the contralateral body. |
| corticospinal fibers | contralateral hemiparesis and typical upper motor neuron findings. It is contralateral because it occurs before the decussation in the medulla. |
| corticobulbar tract | difficulty with contralateral lower facial muscles and hypoglossal nerve functions |
| oculomotor nerve fibers | ipsilateral oculomotor nerve palsy with a drooping eyelid and fixed wide pupil pointed down and out. This leads to diplopia |
It is caused by midbrain infarction as a result of occlusion of the paramedian branches of the posterior cerebral artery or of basilar bifurcation perforating arteries.[2]
Diagnosis[edit | edit source]
Clinical findings mainly eyeball is down and out ipsilateral lateral squint. Ptosis present. Pupil dilated and fixed as the levator palpebrae superioris nerve supply is disrupted. Contralateral hemiplegia CT scan or MRI might help in delineating the cause or the vessel or region of brain involved in stroke.
Management[edit | edit source]
![[icon]](/wiki/File:Wiki_letter_w_cropped.svg){kind=small} | This section is empty. You can help by adding to it. (November 2017) |
History[edit | edit source]
It carries the name of Sir Hermann David Weber, a German-born physician working in London, who described the condition in 1863.[3][4] It is unrelated to Sturge-Weber syndrome, Klippel-Trenaunay-Weber syndrome or Osler-Weber-Rendu syndrome. These conditions are named for his son Frederick Parkes Weber.
See also[edit | edit source]
- Alternating hemiplegia of childhood
- Lateral medullary syndrome
- Lateral pontine syndrome
- Medial medullary syndrome
- Medial pontine syndrome
References[edit | edit source]
External links[edit | edit source]
| Classification | |
|---|---|
| External resources |
|
| This article is a stub. You can help WikiMD by registering to expand it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
