Mycosis Fungoides

Mycosis Fungoides is a type of non-Hodgkin lymphoma that primarily affects the skin. It is the most common form of cutaneous T-cell lymphoma (CTCL) and is characterized by patches, plaques, and tumors on the skin.

Symptoms

The symptoms of Mycosis Fungoides can vary greatly from person to person. The most common symptoms include rashes, itching, and patches or plaques on the skin that may resemble eczema or psoriasis. In later stages, tumors may develop on the skin and the disease may spread to other parts of the body, including the lymph nodes, blood, and internal organs.

Causes

The exact cause of Mycosis Fungoides is unknown. However, it is believed to be caused by a mutation in the T cells, a type of white blood cell that plays a key role in the body's immune response. This mutation causes the T cells to become cancerous and to accumulate in the skin, leading to the symptoms of the disease.

Diagnosis

Diagnosis of Mycosis Fungoides typically involves a skin biopsy, in which a small sample of skin is removed and examined under a microscope. Other tests may include blood tests, imaging tests, and a lymph node biopsy.

Treatment

Treatment for Mycosis Fungoides depends on the stage of the disease and the patient's overall health. Treatment options may include skin-directed therapies, such as topical corticosteroids, retinoids, and phototherapy; systemic therapies, such as chemotherapy and biological therapy; and radiation therapy.

Prognosis

The prognosis for Mycosis Fungoides varies depending on the stage of the disease at diagnosis. Early-stage disease is typically slow-growing and can often be managed with skin-directed therapies. However, advanced-stage disease can be more difficult to treat and may require more aggressive therapies.

See also

• Cutaneous T-cell lymphoma
• Non-Hodgkin lymphoma
• Skin cancer

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