Sperm granuloma

From WikiMD.com Medical Encyclopedia

Sperm Granuloma[edit | edit source]

Sperm granuloma in the epididymis

A sperm granuloma is a lump of extravasated sperm that appears as a result of inflammation. It is a common occurrence following a vasectomy, where sperm leaks from the cut ends of the vas deferens and elicits an immune response. This condition is generally benign and often asymptomatic, but it can sometimes cause pain or discomfort.

Pathophysiology[edit | edit source]

Sperm granulomas form when sperm leak into the surrounding tissue, typically after a vasectomy or injury to the male reproductive system. The body recognizes the sperm as foreign, leading to an inflammatory response. This response involves the formation of a granuloma, which is a collection of immune cells that attempt to wall off the sperm.

The granuloma consists of macrophages, lymphocytes, and fibroblasts, which surround the sperm and form a nodule. Over time, the granuloma may become fibrotic and calcified.

Clinical Presentation[edit | edit source]

Most sperm granulomas are small and asymptomatic. However, in some cases, they can cause:

The pain associated with sperm granulomas is usually due to the inflammatory response and pressure on surrounding tissues.

Diagnosis[edit | edit source]

Diagnosis of a sperm granuloma is typically made through physical examination. A healthcare provider may feel a small, firm nodule in the scrotum. In some cases, ultrasound imaging may be used to differentiate a sperm granuloma from other scrotal masses, such as a hydrocele or epididymal cyst.

Treatment[edit | edit source]

Treatment is often not necessary for sperm granulomas unless they cause significant pain or discomfort. In such cases, options may include:

Prognosis[edit | edit source]

The prognosis for individuals with sperm granulomas is generally excellent. Most granulomas resolve on their own without intervention. Surgical removal is typically successful in alleviating symptoms if necessary.

Related Pages[edit | edit source]


WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD