Erenumab-aooe

What is Erenumab-aooe?

• Erenumab-aooe (Aimovig), is a calcitonin gene-related peptide receptor antagonist.

Aimovig Autoinjector

What are the uses of this medicine?

calcitonin gene related peptide

• Erenumab-aooe (Aimovig), is indicated for the preventive treatment of migraine in adults.

How does this medicine work?

• It binds to the calcitonin gene-related peptide (CGRP) receptor and antagonizes CGRP receptor function thus prevent migraine attacks.

Who Should Not Use this medicine?

• Aimovig is contraindicated in patients with serious hypersensitivity to erenumab-aooe.

Is this medicine FDA approved?

• The United States Food and Drug Administration (FDA) approved the medication for the preventive treatment of migraine in adults on May 17, 2018.

What drug interactions can this medicine cause?

• Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should this medicine be used?

Recommended dosage:

• Recommended dosage is 70 mg once monthly; some patients may benefit from a dosage of 140 mg once monthly.

Administration:

• Aimovig is intended for patient self-administration
• Aimovig is for subcutaneous use only.
• AdministerAimovig in the abdomen, thigh, or upper arm subcutaneously.
• Do not inject into areas where the skin is tender, bruised, red, or hard.

What are the dosage forms and brand names of this medicine?

• Aimovig is a sterile, clear to opalescent, colorless to light yellow solution.
• Aimovig is the brand name.

what to do if i missed a dose?

• If a dose of Aimovig is missed, administer as soon as possible.

what should I know before taking the drug

• The prefilled forms has dry natural rubber (a derivative of latex), which may cause allergic reactions in individuals sensitive to latex.
• Prior to subcutaneous administration, allowAimovig to sit at room temperature for at least 30 minutes protected from direct sunlight
• Do not warm by using a heat source such as hot water or a microwave.
• Do not shake the product.
• Do not use if the solution is cloudy or discolored or contains flakes or particles.
• AdministerAimovig in the abdomen, thigh, or upper arm subcutaneously. Do not inject into areas where the skin is tender, bruised, red, or hard.

What side effects can this medication cause?

The most common side effects of this medicine include:

• pain, redness, or swelling at the injection site and constipation.

Less common,but serious side effects may include:

• Allergic reactions
• Constipation with serious complications
• High blood pressure

What special precautions should I follow?

• Provide guidance to patients and caregivers on proper subcutaneous administration technique, including aseptic technique, and how to use the single-dose prefilled autoinjector or single-dose prefilled syringe. Instruct patients and/or caregivers to read and follow the Instructions for Use each time they useAimovig.
• Advise patients to letAimovig sit at room temperature for at least 30 minutes prior to administration.
• Advise patients to seek immediate medical attention if they experience any symptoms of serious or severe hypersensitivity reactions.
• Advise patients that constipation with serious complications can occur withAimovig and that they should contact their healthcare providers if they experience severe constipation.
• Advise patients that development of hypertension and worsening of pre-existing hypertension can occur withAimovig and that they should contact their healthcare providers if they experience elevation in their blood pressure.
• Advise patients that there is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed toAimovig during pregnancy.
• It is not known if Aimovig passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while usingAimovig.

What to do in case of emergency/overdose?

• In case of overdose, call the poison control helpline of your country. In the United States, call 1-800-222-1222.

• Overdose related information is also available online at poisonhelp.org/help.
• In the event that the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services. In the United States, call 911.
• seek emergency medical care

Can this medicine be used in pregnancy?

• There are no adequate data on the developmental risk associated with the use ofAimovig in pregnant women.
• There is a pregnancy registry for women who takeAimovig. The purpose of this registry is to collect information about your health and your baby's health. You may enroll yourself by calling 1-833-244-4083 or visiting https://www.genesispregnancyregistry.com/. Or you may talk to your doctor about how you can take part in this registry.

Can this medicine be used in children?

• Safety and effectiveness in pediatric patients have not been established.

What should I know about storage and disposal of this medication?

• Store refrigerated at 2°C to 8°C
• If removed from the refrigerator ,should be used within 7 days
• Do not freeze.
• Do not shake

• Dailymed label info on Erenumab-aooe
• FDA Erenumab-aooe

Erenumab-aooe Resources
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