Pioglitazone/alogliptin

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Pioglitazone/alogliptin is a combination drug used for the treatment of Type 2 diabetes. It contains two active ingredients: Pioglitazone, which is a thiazolidinedione, and Alogliptin, which is a DPP-4 inhibitor. This combination is used when diet and exercise alone does not control blood sugar.

Mechanism of Action[edit | edit source]

Pioglitazone works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels. Alogliptin works by increasing the levels of certain natural substances that lower blood sugar when it is high.

Side Effects[edit | edit source]

Common side effects of Pioglitazone/Alogliptin include cold-like symptoms, headache, and back pain. Serious side effects may include heart failure, bladder cancer, and liver problems.

Interactions[edit | edit source]

Pioglitazone/Alogliptin may interact with other medications, including rifampin, gemfibrozil, and insulin or other medications used for diabetes.

Precautions[edit | edit source]

Before taking Pioglitazone/Alogliptin, patients should inform their healthcare provider if they have a history of heart disease, liver disease, or bladder cancer.

Dosage[edit | edit source]

The dosage of Pioglitazone/Alogliptin is based on the patient's medical condition, response to treatment, and other medications they may be taking.

See Also[edit | edit source]

Pioglitazone/alogliptin Resources
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Contributors: Prab R. Tumpati, MD