Wolff-Parkinson-White syndrome

From WikiMD's Wellness Encyclopedia

Wolff-Parkinson-White syndrome (WPW) is a rare congenital heart disease characterized by an abnormal extra electrical pathway in the heart. This condition can lead to periods of rapid heart rate (tachycardia).

Symptoms[edit | edit source]

The most common symptom of WPW syndrome is a rapid heart rate. Other symptoms may include dizziness, shortness of breath, fainting, and in severe cases, cardiac arrest. However, some people with WPW syndrome experience no symptoms at all.

Causes[edit | edit source]

Wolff-Parkinson-White syndrome is caused by a mutation in the PRKAG2 gene. This gene provides instructions for making a protein that is involved in regulating the heart's electrical activity. The mutation leads to the formation of an extra electrical pathway in the heart.

Diagnosis[edit | edit source]

Diagnosis of WPW syndrome is typically made through an electrocardiogram (ECG), which can detect the extra electrical pathway in the heart. Other diagnostic tests may include a Holter monitor, event monitor, or electrophysiological study.

Treatment[edit | edit source]

Treatment for WPW syndrome depends on the severity of the symptoms. In cases where the patient is asymptomatic, no treatment may be necessary. For those with symptoms, treatment options include medication, catheter ablation, or surgery.

Prognosis[edit | edit source]

With appropriate treatment, the prognosis for individuals with WPW syndrome is generally good. However, if left untreated, the condition can lead to serious complications such as atrial fibrillation or sudden cardiac death.

See also[edit | edit source]

Cardiovascular disease A-Z

Most common cardiac diseases

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Contributors: Prab R. Tumpati, MD