2,5-dimethoxy-4-nitroamphetamine

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2,5-dimethoxy-4-nitroamphetamine


2,5-Dimethoxy-4-nitroamphetamine (DOx series), also known as Aleph-6, is a psychedelic drug and a member of the amphetamine family. It is known for its hallucinogenic effects and has been used in psychotherapy and for recreational purposes.

Chemistry[edit | edit source]

2,5-Dimethoxy-4-nitroamphetamine is a substituted amphetamine with a chemical structure consisting of an amphetamine backbone with a nitro group at the 4-position and two methoxy groups at the 2 and 5 positions of the phenyl ring. It is part of the DOx series of psychedelic amphetamines, which also includes 2,5-dimethoxy-4-bromoamphetamine (DOB), 2,5-dimethoxy-4-chloroamphetamine (DOC), and 2,5-dimethoxy-4-iodoamphetamine (DOI).

Pharmacology[edit | edit source]

The exact mechanism of action of 2,5-dimethoxy-4-nitroamphetamine is not fully understood. However, it is believed to act as a serotonin receptor agonist, similar to other psychedelic amphetamines. It may also have activity at other receptor sites in the brain.

Effects[edit | edit source]

The effects of 2,5-dimethoxy-4-nitroamphetamine can vary greatly depending on the dose, individual physiology, and set and setting. Common effects include visual hallucinations, altered thought processes, and a sense of euphoria. Some users also report experiencing synesthesia, a blending of the senses.

Legal Status[edit | edit source]

In many countries, including the United States, 2,5-dimethoxy-4-nitroamphetamine is a controlled substance. It is classified as a Schedule I drug under the Controlled Substances Act in the United States.

See Also[edit | edit source]

Template:Psychoactive drug

Template:Hallucinogen

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Contributors: Prab R. Tumpati, MD